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Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study

Introduction: Recent studies reported a decrease in the incidence of acute myocardial infarction. This favorable evolution does not extend to young women. The interaction between gender, risk factors and myocardial infarction incidence remains controversial. Objective: To compare the evolution of th...

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Autores principales: Loyeau, Aurélie, Benamer, Hakim, Bataille, Sophie, Tepper, Sarah, Boche, Thévy, Lamhaut, Lionel, Pirès, Virginie, Simon, Benoit, Dupas, François, Weisslinger, Lisa, Le Bail, Gaëlle, Allonneau, Alexandre, Juliard, Jean-Michel, Lambert, Yves, Lapostolle, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306837/
https://www.ncbi.nlm.nih.gov/pubmed/30513879
http://dx.doi.org/10.3390/jcm7120509
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author Loyeau, Aurélie
Benamer, Hakim
Bataille, Sophie
Tepper, Sarah
Boche, Thévy
Lamhaut, Lionel
Pirès, Virginie
Simon, Benoit
Dupas, François
Weisslinger, Lisa
Le Bail, Gaëlle
Allonneau, Alexandre
Juliard, Jean-Michel
Lambert, Yves
Lapostolle, Frédéric
author_facet Loyeau, Aurélie
Benamer, Hakim
Bataille, Sophie
Tepper, Sarah
Boche, Thévy
Lamhaut, Lionel
Pirès, Virginie
Simon, Benoit
Dupas, François
Weisslinger, Lisa
Le Bail, Gaëlle
Allonneau, Alexandre
Juliard, Jean-Michel
Lambert, Yves
Lapostolle, Frédéric
author_sort Loyeau, Aurélie
collection PubMed
description Introduction: Recent studies reported a decrease in the incidence of acute myocardial infarction. This favorable evolution does not extend to young women. The interaction between gender, risk factors and myocardial infarction incidence remains controversial. Objective: To compare the evolution of the age pyramid of patients with ST-elevation myocardial infarction (STEMI) according to gender. Methods: Data from patients with STEMI managed in pre-hospital settings prospectively collected in the greater Paris area. Evolution of patient demographics and risk factors was investigated. Results: 28,249 patients with STEMI were included in the registry between 2002 and 2014, 21,883 (77%) males and 6366 (23%) females. The sex ratio did not significantly vary over the study period (p = 0.4). Median patient age was 60.1 years (51.1–73.0) and was significantly different between males and females, respectively 57.9 (50.0–68.3) vs. 72.9 years (58.3–82.2) (p = 0.0004). The median age of males significantly (p = 0.0044) increased from 57.6 (50.1–70.0) in 2002 to 58.1 years (50.5–67.8) in 2014. The median age of females significantly (p = 0.0006) decreased from 73.7 (57.9–81.8) to 69.6 years (57.0–82.4). The median gap between the age of men and women significantly (p = 0.0002) decreased, from 16.1 to 11.5 years. Prevalence of risk factors was unchanged or decreased except for hypertension which significantly increased in males. The rate of STEMI without reported risk factors increased in both males and females. Conclusion: The age of STEMI onset significantly decreased in females, whereas it significantly increased in males. The prevalence of risk factors decreased in males, whereas no significant variation was found in females.
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spelling pubmed-63068372019-01-02 Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study Loyeau, Aurélie Benamer, Hakim Bataille, Sophie Tepper, Sarah Boche, Thévy Lamhaut, Lionel Pirès, Virginie Simon, Benoit Dupas, François Weisslinger, Lisa Le Bail, Gaëlle Allonneau, Alexandre Juliard, Jean-Michel Lambert, Yves Lapostolle, Frédéric J Clin Med Article Introduction: Recent studies reported a decrease in the incidence of acute myocardial infarction. This favorable evolution does not extend to young women. The interaction between gender, risk factors and myocardial infarction incidence remains controversial. Objective: To compare the evolution of the age pyramid of patients with ST-elevation myocardial infarction (STEMI) according to gender. Methods: Data from patients with STEMI managed in pre-hospital settings prospectively collected in the greater Paris area. Evolution of patient demographics and risk factors was investigated. Results: 28,249 patients with STEMI were included in the registry between 2002 and 2014, 21,883 (77%) males and 6366 (23%) females. The sex ratio did not significantly vary over the study period (p = 0.4). Median patient age was 60.1 years (51.1–73.0) and was significantly different between males and females, respectively 57.9 (50.0–68.3) vs. 72.9 years (58.3–82.2) (p = 0.0004). The median age of males significantly (p = 0.0044) increased from 57.6 (50.1–70.0) in 2002 to 58.1 years (50.5–67.8) in 2014. The median age of females significantly (p = 0.0006) decreased from 73.7 (57.9–81.8) to 69.6 years (57.0–82.4). The median gap between the age of men and women significantly (p = 0.0002) decreased, from 16.1 to 11.5 years. Prevalence of risk factors was unchanged or decreased except for hypertension which significantly increased in males. The rate of STEMI without reported risk factors increased in both males and females. Conclusion: The age of STEMI onset significantly decreased in females, whereas it significantly increased in males. The prevalence of risk factors decreased in males, whereas no significant variation was found in females. MDPI 2018-12-03 /pmc/articles/PMC6306837/ /pubmed/30513879 http://dx.doi.org/10.3390/jcm7120509 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Loyeau, Aurélie
Benamer, Hakim
Bataille, Sophie
Tepper, Sarah
Boche, Thévy
Lamhaut, Lionel
Pirès, Virginie
Simon, Benoit
Dupas, François
Weisslinger, Lisa
Le Bail, Gaëlle
Allonneau, Alexandre
Juliard, Jean-Michel
Lambert, Yves
Lapostolle, Frédéric
Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study
title Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study
title_full Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study
title_fullStr Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study
title_full_unstemmed Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study
title_short Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study
title_sort evolution of st-elevation acute myocardial infarction prevalence by gender assessed age pyramid analysis—the piramyd study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306837/
https://www.ncbi.nlm.nih.gov/pubmed/30513879
http://dx.doi.org/10.3390/jcm7120509
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