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Appropriate Imaging Modality for the Etiologic Diagnosis of Congenital Single-Sided Deafness in Children

We aimed to compare the diagnostic yield between temporal bone computed tomography (TBCT) and internal auditory canal MRI (IAC MRI) for the etiologic diagnosis of children with congenital single-sided deafness (SSD) and the evaluation of cochlear implant (CI) candidacy. In the original cohort, 24 su...

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Autores principales: Lee, Sang-Yeon, Kim, Shin Hye, Bae, Yun Jung, Kim, Eun Hee, Koo, Ja-Won, Choi, Byung Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306910/
https://www.ncbi.nlm.nih.gov/pubmed/30518098
http://dx.doi.org/10.3390/jcm7120515
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author Lee, Sang-Yeon
Kim, Shin Hye
Bae, Yun Jung
Kim, Eun Hee
Koo, Ja-Won
Choi, Byung Yoon
author_facet Lee, Sang-Yeon
Kim, Shin Hye
Bae, Yun Jung
Kim, Eun Hee
Koo, Ja-Won
Choi, Byung Yoon
author_sort Lee, Sang-Yeon
collection PubMed
description We aimed to compare the diagnostic yield between temporal bone computed tomography (TBCT) and internal auditory canal MRI (IAC MRI) for the etiologic diagnosis of children with congenital single-sided deafness (SSD) and the evaluation of cochlear implant (CI) candidacy. In the original cohort, 24 subjects with congenital SSD were enrolled and underwent both TBCT and IAC MRI. We recruited an additional 22 consecutive infants with congenital SSD (the supplementary cohort) and evaluated in particular the cochlear nerve (CN) integrity using IAC MRI. Cochlear nerve deficiency (CND) was classified as ‘absent’, ‘small’, and ‘indeterminate’ via mutual comparison between optical and parameters based on the MRI results. The most common etiologies were CND in the original cohort (19 out of 24). Notably, accurate evaluations of CN status (‘small CN’ = 2, ‘indeterminate CN’ = 2), inner ear malformations, and brain abnormalities were possible only with MRI. The ‘indeterminate CN’ tended to be more frequently detected in SSD ears than in unaffected ears. MRI appeared to be more accurate than TBCT in a meticulous differentiation of CN, which is crucial for the selection of appropriate CI candidacy among congenital SSD children. Additionally, we introduced the novel concept of ‘indeterminate CN’, of which the causal relationship with SSD awaits confirmation.
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spelling pubmed-63069102019-01-02 Appropriate Imaging Modality for the Etiologic Diagnosis of Congenital Single-Sided Deafness in Children Lee, Sang-Yeon Kim, Shin Hye Bae, Yun Jung Kim, Eun Hee Koo, Ja-Won Choi, Byung Yoon J Clin Med Article We aimed to compare the diagnostic yield between temporal bone computed tomography (TBCT) and internal auditory canal MRI (IAC MRI) for the etiologic diagnosis of children with congenital single-sided deafness (SSD) and the evaluation of cochlear implant (CI) candidacy. In the original cohort, 24 subjects with congenital SSD were enrolled and underwent both TBCT and IAC MRI. We recruited an additional 22 consecutive infants with congenital SSD (the supplementary cohort) and evaluated in particular the cochlear nerve (CN) integrity using IAC MRI. Cochlear nerve deficiency (CND) was classified as ‘absent’, ‘small’, and ‘indeterminate’ via mutual comparison between optical and parameters based on the MRI results. The most common etiologies were CND in the original cohort (19 out of 24). Notably, accurate evaluations of CN status (‘small CN’ = 2, ‘indeterminate CN’ = 2), inner ear malformations, and brain abnormalities were possible only with MRI. The ‘indeterminate CN’ tended to be more frequently detected in SSD ears than in unaffected ears. MRI appeared to be more accurate than TBCT in a meticulous differentiation of CN, which is crucial for the selection of appropriate CI candidacy among congenital SSD children. Additionally, we introduced the novel concept of ‘indeterminate CN’, of which the causal relationship with SSD awaits confirmation. MDPI 2018-12-04 /pmc/articles/PMC6306910/ /pubmed/30518098 http://dx.doi.org/10.3390/jcm7120515 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Sang-Yeon
Kim, Shin Hye
Bae, Yun Jung
Kim, Eun Hee
Koo, Ja-Won
Choi, Byung Yoon
Appropriate Imaging Modality for the Etiologic Diagnosis of Congenital Single-Sided Deafness in Children
title Appropriate Imaging Modality for the Etiologic Diagnosis of Congenital Single-Sided Deafness in Children
title_full Appropriate Imaging Modality for the Etiologic Diagnosis of Congenital Single-Sided Deafness in Children
title_fullStr Appropriate Imaging Modality for the Etiologic Diagnosis of Congenital Single-Sided Deafness in Children
title_full_unstemmed Appropriate Imaging Modality for the Etiologic Diagnosis of Congenital Single-Sided Deafness in Children
title_short Appropriate Imaging Modality for the Etiologic Diagnosis of Congenital Single-Sided Deafness in Children
title_sort appropriate imaging modality for the etiologic diagnosis of congenital single-sided deafness in children
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306910/
https://www.ncbi.nlm.nih.gov/pubmed/30518098
http://dx.doi.org/10.3390/jcm7120515
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