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Intravascular heavy chain-modification of hyaluronan during endotoxic shock

During inflammation, the covalent linking of the ubiquitous extracellular polysaccharide hyaluronan (HA) with the heavy chains (HC) of the serum protein inter alpha inhibitor (IαI) is exclusively mediated by the enzyme tumor necrosis factor α (TNFα)-stimulated-gene-6 (TSG-6). While significant advan...

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Detalles Bibliográficos
Autores principales: Ni, Kevin, Gill, Amar, Cao, Danting, Koike, Kengo, Schweitzer, Kelly S., Garantziotis, Stavros, Petrache, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307094/
https://www.ncbi.nlm.nih.gov/pubmed/30623115
http://dx.doi.org/10.1016/j.bbrep.2018.12.007