Immune checkpoint inhibitors in MITF family translocation renal cell carcinomas and genetic correlates of exceptional responders

BACKGROUND: Microphthalmia Transcription Factor (MITF)family translocation renal cell carcinoma (tRCC) is a rare RCC subtype harboring TFE3/TFEB translocations. The prognosis in the metastatic (m) setting is poor. Programmed death ligand-1 expression was reported in 90% of cases, prompting us to ana...

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Detalles Bibliográficos
Autores principales: Boilève, A., Carlo, M. I., Barthélémy, P., Oudard, S., Borchiellini, D., Voss, M. H., George, S., Chevreau, C., Landman-Parker, J., Tabone, M-D, Chism, D. D., Amin, A., Bilen, M. A., Bosse, D., Coulomb-L’hermine, A., Su, Xiaoping, Choueiri, T. K., Tannir, Nizar M., Malouf, Gabriel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307255/
https://www.ncbi.nlm.nih.gov/pubmed/30591082
http://dx.doi.org/10.1186/s40425-018-0482-z

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