The addition of simvastatin administration to cold storage solution of explanted whole liver grafts for facing ischemia/reperfusion injury in an area with a low rate of deceased donation: a monocentric randomized controlled double-blinded phase 2 study

BACKGROUND: Liver transplantation is the best treatment for end-stage liver disease. The interruption of the blood supply to the donor liver during cold storage damages the liver, affecting how well the liver will function after transplant. The drug Simvastatin may help to protect donor livers again...

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Detalles Bibliográficos
Autores principales: Pagano, Duilio, Oliva, Elisabetta, Khouzam, Simone, Tuzzolino, Fabio, Cintorino, Davide, Li Petri, Sergio, di Francesco, Fabrizio, Ricotta, Calogero, Bonsignore, Pasquale, Tropea, Alessandro, Calamia, Sergio, Costanzo, Federico, Luca, Angelo, Gruttadauria, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307270/
https://www.ncbi.nlm.nih.gov/pubmed/30587165
http://dx.doi.org/10.1186/s12893-018-0455-7

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