Risk factors and prognosis of acute respiratory distress syndrome following abdominal surgery

Risk factors and prognosis of acute respiratory distress syndrome (ARDS) following abdominal surgery were investigated. Five hundred and thirty-two patients who underwent abdominal surgery in Dongyang People's Hospital from February 2006 to May 2016 were enrolled. Among them, 113 patients had ARDS after surgery and 45 patients died. Those patients were included in observation group. The 419 patients who did not develop ARDS were included in control group, and 11 patients died. General data of patients were statistically analyzed, and the factors with statistical significance were subjected to multivariate logistic regression analysis to analyze the risk factors of ARDS. There was a significant difference in age, infection, trauma-to-surgery time, and prognosis between the two groups (P<0.05). Perioperative blood loss, blood transfusion volume, and fluid volume in the observation group were significantly higher than those in the control group (P<0.05). Heart rate, ratio of PaO2/FiO2, ratio of high (low) blood glucose, levels of procalcitonin (PCT) and albumin (ALB) were significantly different between the two groups. Heart rate, PCT, long-term health assessment (APACHE) II scores were higher in observation group than those in control group (P<0.05). Percentage of hyperglycemic patients, PaO2/FiO2, and ALB were lower in observation group than those in control group (P<0.05). Occurrence of ARDS after abdominal surgery was related to age, infection, heart rate, PaO2/FiO2, and PCT levels (P<0.05). Age, infection, heart rate, PaO2/FiO2, ALB and APACHE II scores were related to the prognosis of patients with ARDS after abdominal surgery (P<0.05). Age, infection, heart rate, PaO2/FiO2, PCT levels, blood loss, blood transfusion volume, and infusion volume may be risk factors for ARDS after abdominal surgery. Age, infection, heart rate, PaO2/FiO2, ALB, and APACHE II scores may be related to prognosis of patients with ARDS after abdominal surgery.