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Arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome

This study aimed to investigate the expression of arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome and their influence on newborns. A total of 348 patients with pregnancy-induced hypertension syndrome (research group) admitted and treated in the First...

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Autores principales: Cao, Yali, Wang, Meichun, Yuan, Yuchao, Li, Cong, Bai, Qinglin, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307481/
https://www.ncbi.nlm.nih.gov/pubmed/30651802
http://dx.doi.org/10.3892/etm.2018.6893
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author Cao, Yali
Wang, Meichun
Yuan, Yuchao
Li, Cong
Bai, Qinglin
Li, Min
author_facet Cao, Yali
Wang, Meichun
Yuan, Yuchao
Li, Cong
Bai, Qinglin
Li, Min
author_sort Cao, Yali
collection PubMed
description This study aimed to investigate the expression of arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome and their influence on newborns. A total of 348 patients with pregnancy-induced hypertension syndrome (research group) admitted and treated in the First People's Hospital of Jining from March 2013 to March 2016 were retrospectively analyzed, and another 156 cases of healthy pregnant women who were physically examined were selected as the control group. Blood gas analysis was performed on pregnant women, and pH value, partial pressure of oxygen (PO2), partial pressure of carbon dioxide (PCO2), bicarbonate radical (HCO3(−)) and base excess (BE) were included as test indexes. Apgar score was made for newborns for neonatal asphyxia. The evaluation was performed at 1, 5, and 10 min after birth to analyze the correlation between the maternal arterial blood pH and the neonatal Apgar score. The pH value, and PO2 and HCO3(−) levels in the research group were lower than those in the control group (p<0.05). PCO2 and BE levels in the research group were higher than those in the control group (p<0.05). The incidence of neonatal mild asphyxia (Apgar score, 4–6 points) and neonatal severe asphyxia (Apgar score, <4 points) in the research group were higher than that in the control group (p<0.05). The Apgar score of newborns was positively correlated with the pH value of the arterial blood of pregnant women. Blood gas analysis in patients with pregnancy-induced hypertension syndrome is useful to a certain extent to evaluate the condition of the patient. The combination of the pH value of the patient and the Apgar score of the newborns may help improve the judgement rate of neonatal asphyxia so as to improve the quality of childbirth by early monitoring and intervention of the newborns.
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spelling pubmed-63074812019-01-16 Arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome Cao, Yali Wang, Meichun Yuan, Yuchao Li, Cong Bai, Qinglin Li, Min Exp Ther Med Articles This study aimed to investigate the expression of arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome and their influence on newborns. A total of 348 patients with pregnancy-induced hypertension syndrome (research group) admitted and treated in the First People's Hospital of Jining from March 2013 to March 2016 were retrospectively analyzed, and another 156 cases of healthy pregnant women who were physically examined were selected as the control group. Blood gas analysis was performed on pregnant women, and pH value, partial pressure of oxygen (PO2), partial pressure of carbon dioxide (PCO2), bicarbonate radical (HCO3(−)) and base excess (BE) were included as test indexes. Apgar score was made for newborns for neonatal asphyxia. The evaluation was performed at 1, 5, and 10 min after birth to analyze the correlation between the maternal arterial blood pH and the neonatal Apgar score. The pH value, and PO2 and HCO3(−) levels in the research group were lower than those in the control group (p<0.05). PCO2 and BE levels in the research group were higher than those in the control group (p<0.05). The incidence of neonatal mild asphyxia (Apgar score, 4–6 points) and neonatal severe asphyxia (Apgar score, <4 points) in the research group were higher than that in the control group (p<0.05). The Apgar score of newborns was positively correlated with the pH value of the arterial blood of pregnant women. Blood gas analysis in patients with pregnancy-induced hypertension syndrome is useful to a certain extent to evaluate the condition of the patient. The combination of the pH value of the patient and the Apgar score of the newborns may help improve the judgement rate of neonatal asphyxia so as to improve the quality of childbirth by early monitoring and intervention of the newborns. D.A. Spandidos 2019-01 2018-10-24 /pmc/articles/PMC6307481/ /pubmed/30651802 http://dx.doi.org/10.3892/etm.2018.6893 Text en Copyright: © Cao et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Cao, Yali
Wang, Meichun
Yuan, Yuchao
Li, Cong
Bai, Qinglin
Li, Min
Arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome
title Arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome
title_full Arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome
title_fullStr Arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome
title_full_unstemmed Arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome
title_short Arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome
title_sort arterial blood gas and acid-base balance in patients with pregnancy-induced hypertension syndrome
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307481/
https://www.ncbi.nlm.nih.gov/pubmed/30651802
http://dx.doi.org/10.3892/etm.2018.6893
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