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The combination of NVP-BEZ235 and rapamycin regulates nasopharyngeal carcinoma cell viability and apoptosis via the PI3K/AKT/mTOR pathway

Nasopharyngeal carcinoma (NPC) is a rare malignancy with a remarkable geographical distribution. Regarding NPC treatment, improving the survival rate of advanced patients seems promising. Phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway deregulatio...

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Detalles Bibliográficos
Autores principales: Luo, Hui, Yu, Yu-Yu, Chen, Hong-Mei, Wu, Wei, Li, Yong, Lin, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307517/
https://www.ncbi.nlm.nih.gov/pubmed/30651769
http://dx.doi.org/10.3892/etm.2018.6896