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Rho signaling pathway enhances proliferation of PASMCs by suppressing nuclear translocation of Smad1 in PAH

Bone morphogenetic protein (BMP) and Rho kinase signaling pathways exert counter regulatory effects on pulmonary artery smooth muscle cell (PASMC) proliferation in pulmonary artery hypertension (PAH). To elucidate the mechanism of this interaction, the present study tested whether Rho kinase activat...

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Detalles Bibliográficos
Autores principales:	Wei, Hongwei, Zhang, Dongqing, Liu, Lili, Xia, Wei, Li, Fuhai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307528/ https://www.ncbi.nlm.nih.gov/pubmed/30603049 http://dx.doi.org/10.3892/etm.2018.6942

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