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Abatacept in combination with methotrexate in Japanese biologic-naive patients with active rheumatoid arthritis: a randomised placebo-controlled phase IV study

OBJECTIVES: To evaluate efficacy and safety of abatacept+methotrexate (MTX) in biologic-naive, anticitrullinated protein antibody (ACPA)-positive Japanese patients with active rheumatoid arthritis (RA) and early erosion versus placebo+MTX. METHODS: In this phase IV, multicentre, double-blind study (...

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Detalles Bibliográficos
Autores principales: Matsubara, Tsukasa, Inoue, Hiroshi, Nakajima, Toshihiro, Tanimura, Kazuhide, Sagawa, Akira, Sato, Yukio, Osano, Kei, Nagano, Shuji, Ueki, Yukitaka, Hanyu, Tadamasa, Hashizume, Koichi, Amano, Norihito, Tanaka, Yoshiya, Takeuchi, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307574/
https://www.ncbi.nlm.nih.gov/pubmed/30622737
http://dx.doi.org/10.1136/rmdopen-2018-000813