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Multiple melanoma in a burns scar

It is well known that up to 2% of chronic burn scar lesions can transform into malignant tumours, however, melanoma formation at these sites is extremely rare. This case report describes a burns case, which progressed to four melanomas in a 78-year-old male patient’s little finger, 40 years after th...

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Detalles Bibliográficos
Autores principales: Cantwell, Phillip, Brooks, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307599/
https://www.ncbi.nlm.nih.gov/pubmed/30580303
http://dx.doi.org/10.1136/bcr-2018-227295
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author Cantwell, Phillip
Brooks, Adrian
author_facet Cantwell, Phillip
Brooks, Adrian
author_sort Cantwell, Phillip
collection PubMed
description It is well known that up to 2% of chronic burn scar lesions can transform into malignant tumours, however, melanoma formation at these sites is extremely rare. This case report describes a burns case, which progressed to four melanomas in a 78-year-old male patient’s little finger, 40 years after the initial incident. The patient underwent 3 mm punch biopsies, then digital amputation of the finger with pathology-proven melanoma. Histopathology investigation demonstrated three melanoma in situ and one invasive melanoma with a Breslow thickness of 1 mm. These findings are rare with few reports of melanoma in burn scars in the literature. This case report highlights the vigilance required from clinicians when performing skin examinations, and the importance of biopsies to newly pigmented lesions.
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spelling pubmed-63075992019-01-04 Multiple melanoma in a burns scar Cantwell, Phillip Brooks, Adrian BMJ Case Rep Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect It is well known that up to 2% of chronic burn scar lesions can transform into malignant tumours, however, melanoma formation at these sites is extremely rare. This case report describes a burns case, which progressed to four melanomas in a 78-year-old male patient’s little finger, 40 years after the initial incident. The patient underwent 3 mm punch biopsies, then digital amputation of the finger with pathology-proven melanoma. Histopathology investigation demonstrated three melanoma in situ and one invasive melanoma with a Breslow thickness of 1 mm. These findings are rare with few reports of melanoma in burn scars in the literature. This case report highlights the vigilance required from clinicians when performing skin examinations, and the importance of biopsies to newly pigmented lesions. BMJ Publishing Group 2018-12-22 /pmc/articles/PMC6307599/ /pubmed/30580303 http://dx.doi.org/10.1136/bcr-2018-227295 Text en © BMJ Publishing Group Limited 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect
Cantwell, Phillip
Brooks, Adrian
Multiple melanoma in a burns scar
title Multiple melanoma in a burns scar
title_full Multiple melanoma in a burns scar
title_fullStr Multiple melanoma in a burns scar
title_full_unstemmed Multiple melanoma in a burns scar
title_short Multiple melanoma in a burns scar
title_sort multiple melanoma in a burns scar
topic Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307599/
https://www.ncbi.nlm.nih.gov/pubmed/30580303
http://dx.doi.org/10.1136/bcr-2018-227295
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