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Multiple melanoma in a burns scar
It is well known that up to 2% of chronic burn scar lesions can transform into malignant tumours, however, melanoma formation at these sites is extremely rare. This case report describes a burns case, which progressed to four melanomas in a 78-year-old male patient’s little finger, 40 years after th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307599/ https://www.ncbi.nlm.nih.gov/pubmed/30580303 http://dx.doi.org/10.1136/bcr-2018-227295 |
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author | Cantwell, Phillip Brooks, Adrian |
author_facet | Cantwell, Phillip Brooks, Adrian |
author_sort | Cantwell, Phillip |
collection | PubMed |
description | It is well known that up to 2% of chronic burn scar lesions can transform into malignant tumours, however, melanoma formation at these sites is extremely rare. This case report describes a burns case, which progressed to four melanomas in a 78-year-old male patient’s little finger, 40 years after the initial incident. The patient underwent 3 mm punch biopsies, then digital amputation of the finger with pathology-proven melanoma. Histopathology investigation demonstrated three melanoma in situ and one invasive melanoma with a Breslow thickness of 1 mm. These findings are rare with few reports of melanoma in burn scars in the literature. This case report highlights the vigilance required from clinicians when performing skin examinations, and the importance of biopsies to newly pigmented lesions. |
format | Online Article Text |
id | pubmed-6307599 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-63075992019-01-04 Multiple melanoma in a burns scar Cantwell, Phillip Brooks, Adrian BMJ Case Rep Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect It is well known that up to 2% of chronic burn scar lesions can transform into malignant tumours, however, melanoma formation at these sites is extremely rare. This case report describes a burns case, which progressed to four melanomas in a 78-year-old male patient’s little finger, 40 years after the initial incident. The patient underwent 3 mm punch biopsies, then digital amputation of the finger with pathology-proven melanoma. Histopathology investigation demonstrated three melanoma in situ and one invasive melanoma with a Breslow thickness of 1 mm. These findings are rare with few reports of melanoma in burn scars in the literature. This case report highlights the vigilance required from clinicians when performing skin examinations, and the importance of biopsies to newly pigmented lesions. BMJ Publishing Group 2018-12-22 /pmc/articles/PMC6307599/ /pubmed/30580303 http://dx.doi.org/10.1136/bcr-2018-227295 Text en © BMJ Publishing Group Limited 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect Cantwell, Phillip Brooks, Adrian Multiple melanoma in a burns scar |
title | Multiple melanoma in a burns scar |
title_full | Multiple melanoma in a burns scar |
title_fullStr | Multiple melanoma in a burns scar |
title_full_unstemmed | Multiple melanoma in a burns scar |
title_short | Multiple melanoma in a burns scar |
title_sort | multiple melanoma in a burns scar |
topic | Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307599/ https://www.ncbi.nlm.nih.gov/pubmed/30580303 http://dx.doi.org/10.1136/bcr-2018-227295 |
work_keys_str_mv | AT cantwellphillip multiplemelanomainaburnsscar AT brooksadrian multiplemelanomainaburnsscar |