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Hospitalisation and life support in the year before and during heart transplantation: a French national study
OBJECTIVE: The objective of this study was to define the characteristics of hospital care use during the year prior to heart transplantation. METHODS: A retrospective cohort of heart transplant recipients registered on the national hospital discharge database between 2010 and 2015 was analysed. RESU...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307614/ https://www.ncbi.nlm.nih.gov/pubmed/30613415 http://dx.doi.org/10.1136/openhrt-2018-000913 |
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author | Cantrelle, Christelle Dorent, Richard Legeai, Camille Damy, Thibaud Bastien, Olivier Tuppin, Philippe |
author_facet | Cantrelle, Christelle Dorent, Richard Legeai, Camille Damy, Thibaud Bastien, Olivier Tuppin, Philippe |
author_sort | Cantrelle, Christelle |
collection | PubMed |
description | OBJECTIVE: The objective of this study was to define the characteristics of hospital care use during the year prior to heart transplantation. METHODS: A retrospective cohort of heart transplant recipients registered on the national hospital discharge database between 2010 and 2015 was analysed. RESULTS: In this cohort of 2379 heart transplant recipients (mean age: 48 years, 74% men), 91% had been admitted at least once, for at least 1 day, to a short-stay hospital during the year before transplantation (mean: 4.3 days), and 84% had at least one cardiovascular diagnosis (heart failure and cardiogenic shock: 60%). At least one intensive care stay was reported for 61% of patients, a rehabilitation stay was reported for 30%, mechanical circulatory support was reported for 12%, and ventilatory support was reported for 15%. The median interval between admission and transplantation was 5 days (interquartile QI–Q3, 0–16). The hospital mortality was higher for patients not hospitalised before transplantation (18% vs 15%). Their transplantation hospitalisation diagnosis, compared with patients hospitalised before transplantation, was more frequently cardiomyopathy (31% vs 27%) or heart failure (28% vs 18%), and less frequently myocardial infarction (1% vs 12%). CONCLUSION: This study demonstrates a high hospitalisation rate before heart transplantation and identifies three groups of patients: 1—patients with a high hospitalisation rate and terminal heart failure requiring circulatory support who experienced at least one intensive care unit stay; 2—patients with a history of hospitalisation, mainly for heart disease, without circulatory support requirement; and 3—patients with no pretransplantation overnight stay. These findings provide useful information to evaluate the medical benefits and needs for transplantation, and identify areas for improvement in heart transplantation listing criteria. |
format | Online Article Text |
id | pubmed-6307614 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-63076142019-01-04 Hospitalisation and life support in the year before and during heart transplantation: a French national study Cantrelle, Christelle Dorent, Richard Legeai, Camille Damy, Thibaud Bastien, Olivier Tuppin, Philippe Open Heart Heart Failure and Cardiomyopathies OBJECTIVE: The objective of this study was to define the characteristics of hospital care use during the year prior to heart transplantation. METHODS: A retrospective cohort of heart transplant recipients registered on the national hospital discharge database between 2010 and 2015 was analysed. RESULTS: In this cohort of 2379 heart transplant recipients (mean age: 48 years, 74% men), 91% had been admitted at least once, for at least 1 day, to a short-stay hospital during the year before transplantation (mean: 4.3 days), and 84% had at least one cardiovascular diagnosis (heart failure and cardiogenic shock: 60%). At least one intensive care stay was reported for 61% of patients, a rehabilitation stay was reported for 30%, mechanical circulatory support was reported for 12%, and ventilatory support was reported for 15%. The median interval between admission and transplantation was 5 days (interquartile QI–Q3, 0–16). The hospital mortality was higher for patients not hospitalised before transplantation (18% vs 15%). Their transplantation hospitalisation diagnosis, compared with patients hospitalised before transplantation, was more frequently cardiomyopathy (31% vs 27%) or heart failure (28% vs 18%), and less frequently myocardial infarction (1% vs 12%). CONCLUSION: This study demonstrates a high hospitalisation rate before heart transplantation and identifies three groups of patients: 1—patients with a high hospitalisation rate and terminal heart failure requiring circulatory support who experienced at least one intensive care unit stay; 2—patients with a history of hospitalisation, mainly for heart disease, without circulatory support requirement; and 3—patients with no pretransplantation overnight stay. These findings provide useful information to evaluate the medical benefits and needs for transplantation, and identify areas for improvement in heart transplantation listing criteria. BMJ Publishing Group 2018-12-09 /pmc/articles/PMC6307614/ /pubmed/30613415 http://dx.doi.org/10.1136/openhrt-2018-000913 Text en © Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | Heart Failure and Cardiomyopathies Cantrelle, Christelle Dorent, Richard Legeai, Camille Damy, Thibaud Bastien, Olivier Tuppin, Philippe Hospitalisation and life support in the year before and during heart transplantation: a French national study |
title | Hospitalisation and life support in the year before and during heart transplantation: a French national study |
title_full | Hospitalisation and life support in the year before and during heart transplantation: a French national study |
title_fullStr | Hospitalisation and life support in the year before and during heart transplantation: a French national study |
title_full_unstemmed | Hospitalisation and life support in the year before and during heart transplantation: a French national study |
title_short | Hospitalisation and life support in the year before and during heart transplantation: a French national study |
title_sort | hospitalisation and life support in the year before and during heart transplantation: a french national study |
topic | Heart Failure and Cardiomyopathies |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307614/ https://www.ncbi.nlm.nih.gov/pubmed/30613415 http://dx.doi.org/10.1136/openhrt-2018-000913 |
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