Vanishing cerebral vasculitis in a patient with Lewy pathology

Immune-mediated mechanisms are involved in the pathogenesis of both cerebral vasculitis and Parkinson's disease (PD, brainstem-predominant Lewy pathology), but the presentation of cerebral vasculitis with comorbid Lewy pathology has not yet been reported. Here we present a case of pathologicall...

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Autores principales: Liapounova, Natalia, Azar, Kamran H., Findlay, J. Max, Lu, Jian-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307664/
https://www.ncbi.nlm.nih.gov/pubmed/29109330
http://dx.doi.org/10.7555/JBR.31.20160119
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author Liapounova, Natalia
Azar, Kamran H.
Findlay, J. Max
Lu, Jian-Qiang
author_facet Liapounova, Natalia
Azar, Kamran H.
Findlay, J. Max
Lu, Jian-Qiang
author_sort Liapounova, Natalia
collection PubMed
description Immune-mediated mechanisms are involved in the pathogenesis of both cerebral vasculitis and Parkinson's disease (PD, brainstem-predominant Lewy pathology), but the presentation of cerebral vasculitis with comorbid Lewy pathology has not yet been reported. Here we present a case of pathologically confirmed vasculitis in a 73-year-old male patient whose postmortem examination revealed Lewy pathology diagnostic of PD. This case study suggests a comorbidity of cerebral vasculitis and Lewy pathology, as well as potential pathogenic interactions between these two disorders with immune-mediated mechanisms.
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spelling pubmed-63076642019-01-11 Vanishing cerebral vasculitis in a patient with Lewy pathology Liapounova, Natalia Azar, Kamran H. Findlay, J. Max Lu, Jian-Qiang J Biomed Res Case Report Immune-mediated mechanisms are involved in the pathogenesis of both cerebral vasculitis and Parkinson's disease (PD, brainstem-predominant Lewy pathology), but the presentation of cerebral vasculitis with comorbid Lewy pathology has not yet been reported. Here we present a case of pathologically confirmed vasculitis in a 73-year-old male patient whose postmortem examination revealed Lewy pathology diagnostic of PD. This case study suggests a comorbidity of cerebral vasculitis and Lewy pathology, as well as potential pathogenic interactions between these two disorders with immune-mediated mechanisms. Editorial Department of Journal of Biomedical Research 2017 /pmc/articles/PMC6307664/ /pubmed/29109330 http://dx.doi.org/10.7555/JBR.31.20160119 Text en
spellingShingle Case Report
Liapounova, Natalia
Azar, Kamran H.
Findlay, J. Max
Lu, Jian-Qiang
Vanishing cerebral vasculitis in a patient with Lewy pathology
title Vanishing cerebral vasculitis in a patient with Lewy pathology
title_full Vanishing cerebral vasculitis in a patient with Lewy pathology
title_fullStr Vanishing cerebral vasculitis in a patient with Lewy pathology
title_full_unstemmed Vanishing cerebral vasculitis in a patient with Lewy pathology
title_short Vanishing cerebral vasculitis in a patient with Lewy pathology
title_sort vanishing cerebral vasculitis in a patient with lewy pathology
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307664/
https://www.ncbi.nlm.nih.gov/pubmed/29109330
http://dx.doi.org/10.7555/JBR.31.20160119
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AT lujianqiang vanishingcerebralvasculitisinapatientwithlewypathology

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