Cargando…

Antitumor activity of the bioreductive prodrug 3-(2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPA-PTX NPs) on MDA-MB-231 cells: in vitro and in vivo

BACKGROUND: 3-(2-Nitrophenyl) propionic acid-paclitaxel (NPPA-PTX) is a paclitaxel (PTX) bioreductive prodrug synthesized by our lab. We hypothesize that NPPA-PTX can self-assemble to form nanoparticles (NPs). MATERIALS AND METHODS: In the present research, the theoretical partition coefficient (Xlo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duan, Xiao-Chuan, Yao, Xin, Zhang, Shuang, Xu, Mei-Qi, Hao, Yan-Li, Li, Zhan-Tao, Zheng, Xiu-Chai, Liu, Man, Li, Zhuo-Yue, Li, Hui, Wang, Jing-Ru, Feng, Zhen-Han, Zhang, Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307681/ https://www.ncbi.nlm.nih.gov/pubmed/30636872 http://dx.doi.org/10.2147/IJN.S186556

Ejemplares similares

The anti-tumor efficacy of 3-(2-Nitrophenyl) propionic acid-paclitaxel (NPPA-PTX): a novel paclitaxel bioreductive prodrug
por: Song, Ping, et al.
Publicado: (2016)

The synergistic antitumor activity of 3-(2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPA-PTX NPs) and anti-PD-L1 antibody inducing immunogenic cell death
por: Duan, Xiao-Chuan, et al.
Publicado: (2021)

Antitumor effects of Xi Huang pills on MDA-MB-231 cells in vitro and in vivo
por: Zheng, Wenxian, et al.
Publicado: (2018)

Antitumor Activity of Chinese Propolis in Human Breast Cancer MCF-7 and MDA-MB-231 Cells
por: Xuan, Hongzhuan, et al.
Publicado: (2014)

Inhibition of FOXO1-mediated autophagy promotes paclitaxel-induced apoptosis of MDA-MB-231 cells
por: Xu, Kaixiang, et al.
Publicado: (2022)

Effects of FSTL1 on cell proliferation in breast cancer cell line MDA-MB-231 and its brain metastatic variant MDA-MB-231-BR
por: An, Jiaqiang, et al.
Publicado: (2017)

Potential Effects of Chrysin on MDA-MB-231 Cells
por: Hong, Teh Ban, et al.
Publicado: (2010)

Loquat (Eriobotrya japonica) leaf extract inhibits the growth of MDA-MB-231 tumors in nude mouse xenografts and invasion of MDA-MB-231 cells
por: You, Mi-Kyoung, et al.
Publicado: (2016)

Citral induced apoptosis in MDA-MB-231 spheroid cells
por: Nigjeh, Siyamak Ebrahimi, et al.
Publicado: (2018)

Shock wave impact on the viability of MDA-MB-231 cells
por: Liao, Yingqian, et al.
Publicado: (2020)

Temporin-GHb of Hylarana guentheri induces apoptosis by the mitochondrial pathway in MDA-MB-231 cells : Temporin-GHb induces MDA-MB-231 cell apoptosis
por: Liu, Yujun, et al.
Publicado: (2022)

Antitumor Activity of Choerospondias axillaris Fruit Extract by Regulating the Expression of SNCAIP and SNCA on MDA-MB-231 Cells
por: Mann, Sonia, et al.
Publicado: (2022)

Combined enzyme/prodrug treatment by genetically engineered AT-MSC exerts synergy and inhibits growth of MDA-MB-231 induced lung metastases
por: Matuskova, Miroslava, et al.
Publicado: (2015)

Action and Signaling of Lysophosphatidylethanolamine in MDA-MB-231 Breast Cancer Cells
por: Park, Soo-Jin, et al.
Publicado: (2014)

Hypoxia regulates stemness of breast cancer MDA-MB-231 cells
por: Xie, Jing, et al.
Publicado: (2016)

Berberine Inhibits MDA-MB-231 Cells by Attenuating Their Inflammatory Responses
por: Zhao, Lina, et al.
Publicado: (2020)

Dehydrocorydaline inhibits the tumorigenesis of breast cancer MDA-MB-231 cells
por: Huang, Ying, et al.
Publicado: (2020)

Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia
por: Guise, Christopher P., et al.
Publicado: (2014)

Antibody-Based Imaging of Bioreductive Prodrug Release in Hypoxia
por: Tosun, Çağla, et al.
Publicado: (2023)

Anti-Axl monoclonal antibodies attenuate the migration of MDA-MB-231 breast cancer cells
por: Chang, Hong, et al.
Publicado: (2021)

Effects of osteopontin inhibition on radiosensitivity of MDA-MB-231 breast cancer cells
por: Hahnel, Antje, et al.
Publicado: (2010)

Anti-Cancer Effect of IN-2001 in MDA-MB-231 Human Breast Cancer
por: Min, Kyung Nan, et al.
Publicado: (2012)

STAT3 Knockdown Induces Tumor Formation by MDA-MB-231 Cells
por: Banerjee, Kasturi, et al.
Publicado: (2018)

Synergistic action of cisplatin and echistatin in MDA-MB-231 breast cancer cells
por: Czarnomysy, Robert, et al.
Publicado: (2016)

Proteomics Profiling of KAIMRC1 in Comparison to MDA-MB231 and MCF-7
por: Alghanem, Bandar, et al.
Publicado: (2020)

Effects of curcumin complexes on MDA-MB-231 breast cancer cell proliferation
por: Mohammed, Fatima, et al.
Publicado: (2020)

A novel UTMD system facilitating nucleic acid delivery into MDA-MB-231 cells
por: Zhang, Hui, et al.
Publicado: (2020)

Antitumor activity of arsenite in combination with tetrandrine against human breast cancer cell line MDA-MB-231 in vitro and in vivo
por: Yuan, Bo, et al.
Publicado: (2018)

Antitumor Potential of Sericite Treatment Mediated by Cell Cycle Arrest in Triple-Negative MDA-MB231 Breast Cancer Cells
por: Kim, Seonhee, et al.
Publicado: (2022)

TFDP3 regulates the apoptosis and autophagy in breast cancer cell line MDA-MB-231
por: Ding, Ling-yu, et al.
Publicado: (2018)

Inhibition of Hypoxia-Induced Cell Motility by p16 in MDA-MB-231 Breast Cancer Cells
por: Li, Liyuan, et al.
Publicado: (2010)

PRIMA-1(MET) Does Not Restore Vitamin D Sensitivity to MDA-MB-231 and MDA-MB-468 Triple-Negative Breast Cancer Cells
por: Kotob, Shadi N., et al.
Publicado: (2023)

Study on the Killing Effect of γδT Cells Activated by Rukangyin on Breast Cancer MDA-MB-231 Cells
por: Chen, Zaiwang, et al.
Publicado: (2021)

Bio-informatics and in Vitro Experiments Reveal the Mechanism of Schisandrin A Against MDA-MB-231 cells
por: Chen, Ling, et al.
Publicado: (2021)

Development of Resistance towards Artesunate in MDA-MB-231 Human Breast Cancer Cells
por: Bachmeier, Beatrice, et al.
Publicado: (2011)

Polyphenols Sensitization Potentiates Susceptibility of MCF-7 and MDA MB-231 Cells to Centchroman
por: Singh, Neetu, et al.
Publicado: (2012)

Phenotypic Switch Induced by Simulated Microgravity on MDA-MB-231 Breast Cancer Cells
por: Masiello, Maria Grazia, et al.
Publicado: (2014)

Effects of Lovastatin on MDA-MB-231 Breast Cancer Cells: An Antibody Microarray Analysis
por: Yang, Tao, et al.
Publicado: (2016)

Optimized Method for Untargeted Metabolomics Analysis of MDA-MB-231 Breast Cancer Cells
por: Peterson, Amanda L., et al.
Publicado: (2016)

Elastin molecular aging promotes MDA‐MB‐231 breast cancer cell invasiveness
por: Salesse, Stéphanie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_smem8kv98m9gkurblm0shmtj9j