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Impact of central and peripheral estrogen treatment on anxiety and depression phenotypes in a mouse model of postmenopausal obesity
Obesity and diabetes increase the risk of depression, and the incidence of these conditions increases rapidly after menopause, but few animal models of postmenopausal obesity have been available. We developed a mouse model of postmenopausal obesity that exhibited anxiety and depressive phenotypes in...
Autores principales: | Wada, Tsutomu, Sameshima, Azusa, Yonezawa, Rika, Morita, Mayuko, Sawakawa, Kanae, Tsuneki, Hiroshi, Sasaoka, Toshiyasu, Saito, Shigeru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307752/ https://www.ncbi.nlm.nih.gov/pubmed/30589890 http://dx.doi.org/10.1371/journal.pone.0209859 |
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