A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn’s disease patients

BACKGROUND: The chronic remitting and relapsing intestinal inflammation characteristic of Crohn’s disease frequently leads to fibrosis and subsequent stenosis of the inflamed region. Approximately a third of all Crohn’s disease patients require resection at some stage in their disease course. As the...

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Detalles Bibliográficos
Autores principales: Li Yim, Andrew Y. F., de Bruyn, Jessica R., Duijvis, Nicolette W., Sharp, Catriona, Ferrero, Enrico, de Jonge, Wouter J., Wildenberg, Manon E., Mannens, Marcel M. A. M., Buskens, Christianne J., D’Haens, Geert R., Henneman, Peter, te Velde, Anje A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307755/
https://www.ncbi.nlm.nih.gov/pubmed/30589872
http://dx.doi.org/10.1371/journal.pone.0209656

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