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DLG5 suppresses breast cancer stem cell‐like characteristics to restore tamoxifen sensitivity by inhibiting TAZ expression

Tamoxifen (TAM) is a primary drug for treatment of estrogen receptor positive breast cancer. However, TAM resistance remains a serious threat to breast cancer patients and may be attributed to increased stemness of breast cancer. Here, we show that discs large homolog 5 (DLG5) expression is down‐reg...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Li, Juan, Li, Pingping, Jiang, Yina, Chen, He, Wang, Ruiqi, Cao, Fang, Liu, Peijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307757/
https://www.ncbi.nlm.nih.gov/pubmed/30450766
http://dx.doi.org/10.1111/jcmm.13954

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