γ‐secretase inhibitor DAPT mitigates cisplatin‐induced acute kidney injury by suppressing Notch1 signaling

Organ toxicity, including kidney injury, limits the use of cisplatin for the treatment of multiple human cancers. Hence, interventions to alleviate cisplatin‐induced nephropathy are of benefit to cancer patients. Recent studies have demonstrated that pharmacological inhibition of the Notch signaling...

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Detalles Bibliográficos
Autores principales: Soni, Hitesh, Matthews, Anberitha T., Pallikkuth, Sandeep, Gangaraju, Rajashekhar, Adebiyi, Adebowale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307805/
https://www.ncbi.nlm.nih.gov/pubmed/30407728
http://dx.doi.org/10.1111/jcmm.13926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307805/
https://www.ncbi.nlm.nih.gov/pubmed/30407728
http://dx.doi.org/10.1111/jcmm.13926

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