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Palmitoylation mediates membrane association of hepatitis E virus ORF3 protein and is required for infectious particle secretion
Hepatitis E virus (HEV) is a positive-strand RNA virus encoding 3 open reading frames (ORF). HEV ORF3 protein is a small, hitherto poorly characterized protein involved in viral particle secretion and possibly other functions. Here, we show that HEV ORF3 protein forms membrane-associated oligomers....
Autores principales: | Gouttenoire, Jérôme, Pollán, Angela, Abrami, Laurence, Oechslin, Noémie, Mauron, Johann, Matter, Maxime, Oppliger, Joël, Szkolnicka, Dagmara, Dao Thi, Viet Loan, van der Goot, F. Gisou, Moradpour, Darius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307819/ https://www.ncbi.nlm.nih.gov/pubmed/30532200 http://dx.doi.org/10.1371/journal.ppat.1007471 |
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