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The planar cell polarity protein VANG-1/Vangl negatively regulates Wnt/β-catenin signaling through a Dvl dependent mechanism

Van Gogh-like (Vangl) and Prickle (Pk) are core components of the non-canonical Wnt planar cell polarity pathway that controls epithelial polarity and cell migration. Studies in vertebrate model systems have suggested that Vangl and Pk may also inhibit signaling through the canonical Wnt/β-catenin p...

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Detalles Bibliográficos
Autores principales:	Mentink, Remco A., Rella, Lorenzo, Radaszkiewicz, Tomasz W., Gybel, Tomáš, Betist, Marco C., Bryja, Vitězslav, Korswagen, Hendrik C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307821/ https://www.ncbi.nlm.nih.gov/pubmed/30532125 http://dx.doi.org/10.1371/journal.pgen.1007840

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