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Cardiac‐specific Mst1 deficiency inhibits ROS‐mediated JNK signalling to alleviate Ang II‐induced cardiomyocyte apoptosis
Apoptosis is associated with various myocardial diseases. Angiotensin II (Ang II) plays a central role in the pathogenesis of RAAS‐triggered cardiac apoptosis. Our previous studies showed that mammalian Ste20‐like kinase 1 (Mst1) aggravates cardiac dysfunction in cardiomyocyte under pathological con...
Autores principales: | Cheng, Zheng, Zhang, Mingming, Hu, Jianqiang, Lin, Jie, Feng, Xinyu, Wang, Shanjie, Wang, Tingting, Gao, Erhe, Wang, Haichang, Sun, Dongdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307828/ https://www.ncbi.nlm.nih.gov/pubmed/30338935 http://dx.doi.org/10.1111/jcmm.13958 |
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