Aquaporin-4-dependent glymphatic solute transport in the rodent brain

The glymphatic system is a brain-wide clearance pathway; its impairment contributes to the accumulation of amyloid-β. Influx of cerebrospinal fluid (CSF) depends upon the expression and perivascular localization of the astroglial water channel aquaporin-4 (AQP4). Prompted by a recent failure to find...

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Detalles Bibliográficos
Autores principales: Mestre, Humberto, Hablitz, Lauren M, Xavier, Anna LR, Feng, Weixi, Zou, Wenyan, Pu, Tinglin, Monai, Hiromu, Murlidharan, Giridhar, Castellanos Rivera, Ruth M, Simon, Matthew J, Pike, Martin M, Plá, Virginia, Du, Ting, Kress, Benjamin T, Wang, Xiaowen, Plog, Benjamin A, Thrane, Alexander S, Lundgaard, Iben, Abe, Yoichiro, Yasui, Masato, Thomas, John H, Xiao, Ming, Hirase, Hajime, Asokan, Aravind, Iliff, Jeffrey J, Nedergaard, Maiken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307855/
https://www.ncbi.nlm.nih.gov/pubmed/30561329
http://dx.doi.org/10.7554/eLife.40070

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