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Dynamic multifactor hubs interact transiently with sites of active transcription in Drosophila embryos
The regulation of transcription requires the coordination of numerous activities on DNA, yet how transcription factors mediate these activities remains poorly understood. Here, we use lattice light-sheet microscopy to integrate single-molecule and high-speed 4D imaging in developing Drosophila embry...
Autores principales: | Mir, Mustafa, Stadler, Michael R, Ortiz, Stephan A, Hannon, Colleen E, Harrison, Melissa M, Darzacq, Xavier, Eisen, Michael B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307861/ https://www.ncbi.nlm.nih.gov/pubmed/30589412 http://dx.doi.org/10.7554/eLife.40497 |
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