Cargando…
Leukemia development initiated by deletion of RBP-J: mouse strain, deletion efficiency and cell of origin
Conditional deletion of RBP-J, the major transcriptional effector of Notch signaling, specifically within renin-expressing cells leads to the development of B-cell leukemia. However, the influence of contributing factors such as mouse strain, cell of origin and Cre recombinase copy number are unknow...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307899/ https://www.ncbi.nlm.nih.gov/pubmed/30467111 http://dx.doi.org/10.1242/dmm.036731 |