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Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of Caenorhabditis elegans and its functional response to drugs
Muscle strength is a key clinical parameter used to monitor the progression of human muscular dystrophies, including Duchenne and Becker muscular dystrophies. Although Caenorhabditis elegans is an established genetic model for studying the mechanisms and treatments of muscular dystrophies, analogous...
Autores principales: | Hewitt, Jennifer E., Pollard, Amelia K., Lesanpezeshki, Leila, Deane, Colleen S., Gaffney, Christopher J., Etheridge, Timothy, Szewczyk, Nathaniel J., Vanapalli, Siva A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307913/ https://www.ncbi.nlm.nih.gov/pubmed/30396907 http://dx.doi.org/10.1242/dmm.036137 |
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