A three-year-old boy with hypodipsic hypernatremia syndrome

We describe a three-year-old boy who had a growth and psychomotor retardation associated with inappropriate lack of thirst and vasopressin secretion in the presence of chronic plasma hyperosmolarity. Computed brain tomography revealed bilateral supratentorial sub-ependymal and cortical calcification...

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Detalles Bibliográficos
Autores principales: Iraqi, Bousayna, Abilkassem, Rachid, Dini, Nezha, Agadr, Aomar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307918/
https://www.ncbi.nlm.nih.gov/pubmed/30627311
http://dx.doi.org/10.11604/pamj.2018.30.250.12263
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author Iraqi, Bousayna
Abilkassem, Rachid
Dini, Nezha
Agadr, Aomar
author_facet Iraqi, Bousayna
Abilkassem, Rachid
Dini, Nezha
Agadr, Aomar
author_sort Iraqi, Bousayna
collection PubMed
description We describe a three-year-old boy who had a growth and psychomotor retardation associated with inappropriate lack of thirst and vasopressin secretion in the presence of chronic plasma hyperosmolarity. Computed brain tomography revealed bilateral supratentorial sub-ependymal and cortical calcifications. Dissociation in the plasma vasopressin response to osmotic change was demonstrated in this patient. Treatment with a vasopressin analogue, desamino-D-arginine vasopressin (DDAVP) and forced intake of water restored plasma osmolality and serum sodium levels to normal.
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spelling pubmed-63079182019-01-09 A three-year-old boy with hypodipsic hypernatremia syndrome Iraqi, Bousayna Abilkassem, Rachid Dini, Nezha Agadr, Aomar Pan Afr Med J Case Report We describe a three-year-old boy who had a growth and psychomotor retardation associated with inappropriate lack of thirst and vasopressin secretion in the presence of chronic plasma hyperosmolarity. Computed brain tomography revealed bilateral supratentorial sub-ependymal and cortical calcifications. Dissociation in the plasma vasopressin response to osmotic change was demonstrated in this patient. Treatment with a vasopressin analogue, desamino-D-arginine vasopressin (DDAVP) and forced intake of water restored plasma osmolality and serum sodium levels to normal. The African Field Epidemiology Network 2018-08-06 /pmc/articles/PMC6307918/ /pubmed/30627311 http://dx.doi.org/10.11604/pamj.2018.30.250.12263 Text en © Bousayna Iraqi et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Iraqi, Bousayna
Abilkassem, Rachid
Dini, Nezha
Agadr, Aomar
A three-year-old boy with hypodipsic hypernatremia syndrome
title A three-year-old boy with hypodipsic hypernatremia syndrome
title_full A three-year-old boy with hypodipsic hypernatremia syndrome
title_fullStr A three-year-old boy with hypodipsic hypernatremia syndrome
title_full_unstemmed A three-year-old boy with hypodipsic hypernatremia syndrome
title_short A three-year-old boy with hypodipsic hypernatremia syndrome
title_sort three-year-old boy with hypodipsic hypernatremia syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307918/
https://www.ncbi.nlm.nih.gov/pubmed/30627311
http://dx.doi.org/10.11604/pamj.2018.30.250.12263
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