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Syndrome de résistance à l’Adrénocorticotrophine Hormone (ACTH): à propos d’un cas
Adrenocorticotropic hormone (ACTH) insensitivity syndrome is one of the rare causes of adrenal insufficiency in children. All described inherited ACTH insensitivity forms are of autosomal recessive origin. In our resource-poor Countries, many of these rare diseases are ignored or not diagnosed due t...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307927/ https://www.ncbi.nlm.nih.gov/pubmed/30627305 http://dx.doi.org/10.11604/pamj.2018.30.244.15541 |
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author | Houngbadji, Morgiane Solange Tognidé Sêlomin Niang, Babacar Boiro, Djibril Mbaye, Aminata Seck, Abdoulaye Ndongo, Abdoulaye Aliou Ly, Indou Deme Ndiaye, Ousmane |
author_facet | Houngbadji, Morgiane Solange Tognidé Sêlomin Niang, Babacar Boiro, Djibril Mbaye, Aminata Seck, Abdoulaye Ndongo, Abdoulaye Aliou Ly, Indou Deme Ndiaye, Ousmane |
author_sort | Houngbadji, Morgiane Solange Tognidé Sêlomin |
collection | PubMed |
description | Adrenocorticotropic hormone (ACTH) insensitivity syndrome is one of the rare causes of adrenal insufficiency in children. All described inherited ACTH insensitivity forms are of autosomal recessive origin. In our resource-poor Countries, many of these rare diseases are ignored or not diagnosed due to inadequate technical equipments. We report the case of a 4-month old infant hospitalized for refractory hypoglycaemias. Despite the patient had generalized and severe melanodermia, digestive disorders and ion channel disorders the diagnosis of cortisol deficiency was only diagnosed retrospectively during respiratory arrest with favorable outcome under hydrocortisone therapy. This study aims to highlight the clinical, laboratory and therapeutic features of peripheral cortisol deficiency, without enzymatic blocks, including this adrenocorticotropic hormone (ACTH) insensitivity syndrome. |
format | Online Article Text |
id | pubmed-6307927 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-63079272019-01-09 Syndrome de résistance à l’Adrénocorticotrophine Hormone (ACTH): à propos d’un cas Houngbadji, Morgiane Solange Tognidé Sêlomin Niang, Babacar Boiro, Djibril Mbaye, Aminata Seck, Abdoulaye Ndongo, Abdoulaye Aliou Ly, Indou Deme Ndiaye, Ousmane Pan Afr Med J Case Report Adrenocorticotropic hormone (ACTH) insensitivity syndrome is one of the rare causes of adrenal insufficiency in children. All described inherited ACTH insensitivity forms are of autosomal recessive origin. In our resource-poor Countries, many of these rare diseases are ignored or not diagnosed due to inadequate technical equipments. We report the case of a 4-month old infant hospitalized for refractory hypoglycaemias. Despite the patient had generalized and severe melanodermia, digestive disorders and ion channel disorders the diagnosis of cortisol deficiency was only diagnosed retrospectively during respiratory arrest with favorable outcome under hydrocortisone therapy. This study aims to highlight the clinical, laboratory and therapeutic features of peripheral cortisol deficiency, without enzymatic blocks, including this adrenocorticotropic hormone (ACTH) insensitivity syndrome. The African Field Epidemiology Network 2018-08-02 /pmc/articles/PMC6307927/ /pubmed/30627305 http://dx.doi.org/10.11604/pamj.2018.30.244.15541 Text en © Morgiane Solange Tognidé Sêlomin Houngbadji et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Houngbadji, Morgiane Solange Tognidé Sêlomin Niang, Babacar Boiro, Djibril Mbaye, Aminata Seck, Abdoulaye Ndongo, Abdoulaye Aliou Ly, Indou Deme Ndiaye, Ousmane Syndrome de résistance à l’Adrénocorticotrophine Hormone (ACTH): à propos d’un cas |
title | Syndrome de résistance à l’Adrénocorticotrophine Hormone (ACTH): à propos d’un cas |
title_full | Syndrome de résistance à l’Adrénocorticotrophine Hormone (ACTH): à propos d’un cas |
title_fullStr | Syndrome de résistance à l’Adrénocorticotrophine Hormone (ACTH): à propos d’un cas |
title_full_unstemmed | Syndrome de résistance à l’Adrénocorticotrophine Hormone (ACTH): à propos d’un cas |
title_short | Syndrome de résistance à l’Adrénocorticotrophine Hormone (ACTH): à propos d’un cas |
title_sort | syndrome de résistance à l’adrénocorticotrophine hormone (acth): à propos d’un cas |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307927/ https://www.ncbi.nlm.nih.gov/pubmed/30627305 http://dx.doi.org/10.11604/pamj.2018.30.244.15541 |
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