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Gas chromatography-mass spectrometry method for determination of β-propiolactone in human inactivated rabies vaccine and its hydrolysis analysis

A simple method was established for the determination of β-propiolactone (BPL) in human inactivated rabies vaccine by gas chromatography-mass spectrometry (GC-MS). The determination was performed on an Agilent HP-INNOWAX (30 m × 0.32 mm i.d., 0.25 µm) capillary column at the temperature of 80 °C. El...

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Detalles Bibliográficos
Autores principales: Lei, Shuo, Gao, Xun, Sun, Yang, Yu, Xiangyong, Zhao, Longshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308022/
https://www.ncbi.nlm.nih.gov/pubmed/30595943
http://dx.doi.org/10.1016/j.jpha.2018.06.003

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