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Gas chromatography-mass spectrometry method for determination of β-propiolactone in human inactivated rabies vaccine and its hydrolysis analysis
A simple method was established for the determination of β-propiolactone (BPL) in human inactivated rabies vaccine by gas chromatography-mass spectrometry (GC-MS). The determination was performed on an Agilent HP-INNOWAX (30 m × 0.32 mm i.d., 0.25 µm) capillary column at the temperature of 80 °C. El...
Autores principales: | Lei, Shuo, Gao, Xun, Sun, Yang, Yu, Xiangyong, Zhao, Longshan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308022/ https://www.ncbi.nlm.nih.gov/pubmed/30595943 http://dx.doi.org/10.1016/j.jpha.2018.06.003 |
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