Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates

OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) risk begins in utero in offspring of obese mothers. A critical unmet need in this field is to understand the pathways and biomarkers underlying fetal hepatic lipotoxicity and whether maternal dietary intervention during pregnancy is an effective c...

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Detalles Bibliográficos
Autores principales: Wesolowski, Stephanie R., Mulligan, Christopher M., Janssen, Rachel C., Baker, Peter R., Bergman, Bryan C., D'Alessandro, Angelo, Nemkov, Travis, Maclean, Kenneth N., Jiang, Hua, Dean, Tyler A., Takahashi, Diana L., Kievit, Paul, McCurdy, Carrie E., Aagaard, Kjersti M., Friedman, Jacob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308036/
https://www.ncbi.nlm.nih.gov/pubmed/30337225
http://dx.doi.org/10.1016/j.molmet.2018.09.008

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