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Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy

Elevated glycolysis remains a universal and primary character of cancer metabolism, which deeply depends on dysregulated metabolic enzymes. Lactate dehydrogenase A (LDHA) facilitates glycolytic process by converting pyruvate to lactate. Numerous researches demonstrate LDHA has an aberrantly high exp...

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Detalles Bibliográficos
Autores principales: Feng, Yangbo, Xiong, Yanlu, Qiao, Tianyun, Li, Xiaofei, Jia, Lintao, Han, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308051/
https://www.ncbi.nlm.nih.gov/pubmed/30403008
http://dx.doi.org/10.1002/cam4.1820

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