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Naïve CD8(+) T-Cells Engage a Versatile Metabolic Program Upon Activation in Humans and Differ Energetically From Memory CD8(+) T-Cells
Background: Characterization of the intracellular biochemical processes that regulate the generation and maintenance of effector and memory CD8(+) T-cells from naïve precursors is essential for our understanding of adaptive immune responses and the development of immunotherapies. However, the metabo...
Autores principales: | Nicoli, Francesco, Papagno, Laura, Frere, Justin J., Cabral-Piccin, Mariela Pires, Clave, Emmanuel, Gostick, Emma, Toubert, Antoine, Price, David A., Caputo, Antonella, Appay, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308131/ https://www.ncbi.nlm.nih.gov/pubmed/30619240 http://dx.doi.org/10.3389/fimmu.2018.02736 |
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