CD9(+) Regulatory B Cells Induce T Cell Apoptosis via IL-10 and Are Reduced in Severe Asthmatic Patients

CD9 was recently identified as a marker of murine IL-10-competent regulatory B cells. Functional impairments or defects in CD9(+) IL-10-secreting regulatory B cells are associated with enhanced asthma-like inflammation and airway hyperresponsiveness. In mouse models, all asthma-related features can...

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Detalles Bibliográficos
Autores principales: Brosseau, Carole, Durand, Maxim, Colas, Luc, Durand, Eugénie, Foureau, Aurore, Cheminant, Marie-Aude, Bouchaud, Gregory, Castan, Laure, Klein, Martin, Magnan, Antoine, Brouard, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308143/
https://www.ncbi.nlm.nih.gov/pubmed/30622536
http://dx.doi.org/10.3389/fimmu.2018.03034

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