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Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with Lewy bodies

Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are neurodegenerative disorders of the aging population characterized by the accumulation of α-synuclein (α-syn). The mechanisms triggering α-syn toxicity are not completely understood, however, c-terminus truncation of α-syn by proteases...

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Detalles Bibliográficos
Autores principales:	Hassen, Getaw Worku, Kesner, Leo, Stracher, Alfred, Shulman, Abraham, Rockenstein, Edward, Mante, Michael, Adame, Anthony, Overk, Cassia, Rissman, Robert A., Masliah, Eliezer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308237/ https://www.ncbi.nlm.nih.gov/pubmed/30591714 http://dx.doi.org/10.1038/s41598-018-35729-1

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