IRAK-M Deficiency Exacerbates Ischemic Neurovascular Injuries in Experimental Stroke Mice

Background: Innate immune response to neuronal death is one of the key events of the pathogenesis of ischemic brain injury. Interleukin-1 receptor-associated kinase (IRAK)-M, encoded by gene Irak3, negatively regulates toll-like receptor signaling by interacting with the MyD88–IRAK-4–IRAK-1 complex...

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Detalles Bibliográficos
Autores principales: Lyu, Chenfei, Zhang, Yongfang, Gu, Minhua, Huang, Yusheng, Liu, Guanghui, Wang, Chen, Li, Miaodan, Chen, Shumin, Pan, Suyue, Gu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308305/
https://www.ncbi.nlm.nih.gov/pubmed/30622459
http://dx.doi.org/10.3389/fncel.2018.00504

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