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Difference in Mono-O-Glucosylation of Ras Subtype GTPases Between Toxin A and Toxin B From Clostridioides difficile Strain 10463 and Lethal Toxin From Clostridium sordellii Strain 6018

Clostridioides difficile toxin A (TcdA) and Toxin B (TcdB) trigger inflammasome activation with caspase-1 activation in cultured cells, which in turn induce the release of IL-6, IFN-γ, and IL-8. Release of these proinflammatory responses is positively regulated by Ras-GTPases, which leads to the hyp...

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Detalles Bibliográficos
Autores principales:	Genth, Harald, Junemann, Johannes, Lämmerhirt, Chantal M., Lücke, Arlen-Celina, Schelle, Ilona, Just, Ingo, Gerhard, Ralf, Pich, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308379/ https://www.ncbi.nlm.nih.gov/pubmed/30622517 http://dx.doi.org/10.3389/fmicb.2018.03078

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