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Tuberculosis Burden in Ethiopia from 1990 to 2016: Evidence from the Global Burden of Diseases 2016 Study

BACKGROUND: The burden of Tuberculosis (TB) has not been comprehensively evaluated over the last 25 years in Ethiopia. In this study, we used the 2016 Global Burden of Diseases, Injuries and Risk Factors (GBD) data to analyze the incidence, prevalence and mortality rates of tuberculosis (TB) in Ethi...

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Autores principales: Deribew, Amare, Deribe, Kebede, Dejene, Tariku, Tessema, Gizachew Assefa, Melaku, Yohannes Adama, Lakew, Yihune, Amare, Azmeraw T, Bekele, Tolessa, Abera, Semaw F, Dessalegn, Muluken, Kumsa, Andargachew, Assefa, Yibeltal, Kyu, Hmwe, Glenn, Scott D, Misganaw, Awoke, Biadgilign, Sibhatu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research and Publications Office of Jimma University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308773/
https://www.ncbi.nlm.nih.gov/pubmed/30607066
http://dx.doi.org/10.4314/ejhs.v28i5.2
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author Deribew, Amare
Deribe, Kebede
Dejene, Tariku
Tessema, Gizachew Assefa
Melaku, Yohannes Adama
Lakew, Yihune
Amare, Azmeraw T
Bekele, Tolessa
Abera, Semaw F
Dessalegn, Muluken
Kumsa, Andargachew
Assefa, Yibeltal
Kyu, Hmwe
Glenn, Scott D
Misganaw, Awoke
Biadgilign, Sibhatu
author_facet Deribew, Amare
Deribe, Kebede
Dejene, Tariku
Tessema, Gizachew Assefa
Melaku, Yohannes Adama
Lakew, Yihune
Amare, Azmeraw T
Bekele, Tolessa
Abera, Semaw F
Dessalegn, Muluken
Kumsa, Andargachew
Assefa, Yibeltal
Kyu, Hmwe
Glenn, Scott D
Misganaw, Awoke
Biadgilign, Sibhatu
author_sort Deribew, Amare
collection PubMed
description BACKGROUND: The burden of Tuberculosis (TB) has not been comprehensively evaluated over the last 25 years in Ethiopia. In this study, we used the 2016 Global Burden of Diseases, Injuries and Risk Factors (GBD) data to analyze the incidence, prevalence and mortality rates of tuberculosis (TB) in Ethiopia over the last 26 years. METHODS: The GBD 2016 is a mathematical modeling using different data source for Ethiopia such as verbal autopsy (VA), prevalence surveys and annual case notifications. Age and sex specific causes of death for TB were estimated using the Cause of Death Ensemble Modeling (CODEm). We used the available data such as annual notifications and prevalence surveys as an input to estimate incidence and prevalence rates respectively using DisMod-MR 2.1, a Bayesian meta-regression tool. RESULTS: In 2016, we estimated 219,186 (95%UI: 182,977–265,292) new, 151,602 (95% UI: 126,054–180,976) prevalent TB cases and 48,910(95% UI: 40,310–58,195) TB deaths. The age-standardized TB incidence rate decreased from 201.6/100,000 to 88.5/100,000 (with a total decline of 56%) between 1990 to 2016. Similarly, the age-standardized TB mortality rate declined from 393.8/100,000 to 100/100,000 between 1990 and 2016(with a total decline of 75%). CONCLUSIONS: Ethiopia has achieved the 50% reduction of most of the Millennium Development Goals (MDGs) targets related to TB. However, the decline of TB incidence and prevalence rates has been comparatively slow. The country should strengthen the TB case detection and treatment programs at community level to achieve its targets during the Sustainable Development Program (SDGs)-era.
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spelling pubmed-63087732019-01-03 Tuberculosis Burden in Ethiopia from 1990 to 2016: Evidence from the Global Burden of Diseases 2016 Study Deribew, Amare Deribe, Kebede Dejene, Tariku Tessema, Gizachew Assefa Melaku, Yohannes Adama Lakew, Yihune Amare, Azmeraw T Bekele, Tolessa Abera, Semaw F Dessalegn, Muluken Kumsa, Andargachew Assefa, Yibeltal Kyu, Hmwe Glenn, Scott D Misganaw, Awoke Biadgilign, Sibhatu Ethiop J Health Sci Original Article BACKGROUND: The burden of Tuberculosis (TB) has not been comprehensively evaluated over the last 25 years in Ethiopia. In this study, we used the 2016 Global Burden of Diseases, Injuries and Risk Factors (GBD) data to analyze the incidence, prevalence and mortality rates of tuberculosis (TB) in Ethiopia over the last 26 years. METHODS: The GBD 2016 is a mathematical modeling using different data source for Ethiopia such as verbal autopsy (VA), prevalence surveys and annual case notifications. Age and sex specific causes of death for TB were estimated using the Cause of Death Ensemble Modeling (CODEm). We used the available data such as annual notifications and prevalence surveys as an input to estimate incidence and prevalence rates respectively using DisMod-MR 2.1, a Bayesian meta-regression tool. RESULTS: In 2016, we estimated 219,186 (95%UI: 182,977–265,292) new, 151,602 (95% UI: 126,054–180,976) prevalent TB cases and 48,910(95% UI: 40,310–58,195) TB deaths. The age-standardized TB incidence rate decreased from 201.6/100,000 to 88.5/100,000 (with a total decline of 56%) between 1990 to 2016. Similarly, the age-standardized TB mortality rate declined from 393.8/100,000 to 100/100,000 between 1990 and 2016(with a total decline of 75%). CONCLUSIONS: Ethiopia has achieved the 50% reduction of most of the Millennium Development Goals (MDGs) targets related to TB. However, the decline of TB incidence and prevalence rates has been comparatively slow. The country should strengthen the TB case detection and treatment programs at community level to achieve its targets during the Sustainable Development Program (SDGs)-era. Research and Publications Office of Jimma University 2018-09 /pmc/articles/PMC6308773/ /pubmed/30607066 http://dx.doi.org/10.4314/ejhs.v28i5.2 Text en © 2018 Amare Deribew, et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Article
Deribew, Amare
Deribe, Kebede
Dejene, Tariku
Tessema, Gizachew Assefa
Melaku, Yohannes Adama
Lakew, Yihune
Amare, Azmeraw T
Bekele, Tolessa
Abera, Semaw F
Dessalegn, Muluken
Kumsa, Andargachew
Assefa, Yibeltal
Kyu, Hmwe
Glenn, Scott D
Misganaw, Awoke
Biadgilign, Sibhatu
Tuberculosis Burden in Ethiopia from 1990 to 2016: Evidence from the Global Burden of Diseases 2016 Study
title Tuberculosis Burden in Ethiopia from 1990 to 2016: Evidence from the Global Burden of Diseases 2016 Study
title_full Tuberculosis Burden in Ethiopia from 1990 to 2016: Evidence from the Global Burden of Diseases 2016 Study
title_fullStr Tuberculosis Burden in Ethiopia from 1990 to 2016: Evidence from the Global Burden of Diseases 2016 Study
title_full_unstemmed Tuberculosis Burden in Ethiopia from 1990 to 2016: Evidence from the Global Burden of Diseases 2016 Study
title_short Tuberculosis Burden in Ethiopia from 1990 to 2016: Evidence from the Global Burden of Diseases 2016 Study
title_sort tuberculosis burden in ethiopia from 1990 to 2016: evidence from the global burden of diseases 2016 study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308773/
https://www.ncbi.nlm.nih.gov/pubmed/30607066
http://dx.doi.org/10.4314/ejhs.v28i5.2
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