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Revisiting Risk Governance of GM Plants: The Need to Consider New and Emerging Gene-Editing Techniques

New and emerging gene-editing techniques make it possible to target specific genes in species with greater speed and specificity than previously possible. Of major relevance for plant breeding, regulators and scientists are discussing how to regulate products developed using these gene-editing techn...

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Autores principales: Agapito-Tenfen, Sarah Z., Okoli, Arinze S., Bernstein, Michael J., Wikmark, Odd-Gunnar, Myhr, Anne I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308909/
https://www.ncbi.nlm.nih.gov/pubmed/30622546
http://dx.doi.org/10.3389/fpls.2018.01874
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author Agapito-Tenfen, Sarah Z.
Okoli, Arinze S.
Bernstein, Michael J.
Wikmark, Odd-Gunnar
Myhr, Anne I.
author_facet Agapito-Tenfen, Sarah Z.
Okoli, Arinze S.
Bernstein, Michael J.
Wikmark, Odd-Gunnar
Myhr, Anne I.
author_sort Agapito-Tenfen, Sarah Z.
collection PubMed
description New and emerging gene-editing techniques make it possible to target specific genes in species with greater speed and specificity than previously possible. Of major relevance for plant breeding, regulators and scientists are discussing how to regulate products developed using these gene-editing techniques. Such discussions include whether to adopt or adapt the current framework for GMO risk governance in evaluating the impacts of gene-edited plants, and derived products, on the environment, human and animal health and society. Product classification or definition is one of several aspects of the current framework being criticized. Further, knowledge gaps related to risk assessments of gene-edited organisms—for example of target and off-target effects of intervention in plant genomes—are also of concern. Resolving these and related aspects of the current framework will involve addressing many subjective, value-laden positions, for example how to specify protection goals through ecosystem service approaches. A process informed by responsible research and innovation practices, involving a broader community of people, organizations, experts, and interest groups, could help scientists, regulators, and other stakeholders address these complex, value-laden concerns related to gene-editing of plants with and for society.
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spelling pubmed-63089092019-01-08 Revisiting Risk Governance of GM Plants: The Need to Consider New and Emerging Gene-Editing Techniques Agapito-Tenfen, Sarah Z. Okoli, Arinze S. Bernstein, Michael J. Wikmark, Odd-Gunnar Myhr, Anne I. Front Plant Sci Plant Science New and emerging gene-editing techniques make it possible to target specific genes in species with greater speed and specificity than previously possible. Of major relevance for plant breeding, regulators and scientists are discussing how to regulate products developed using these gene-editing techniques. Such discussions include whether to adopt or adapt the current framework for GMO risk governance in evaluating the impacts of gene-edited plants, and derived products, on the environment, human and animal health and society. Product classification or definition is one of several aspects of the current framework being criticized. Further, knowledge gaps related to risk assessments of gene-edited organisms—for example of target and off-target effects of intervention in plant genomes—are also of concern. Resolving these and related aspects of the current framework will involve addressing many subjective, value-laden positions, for example how to specify protection goals through ecosystem service approaches. A process informed by responsible research and innovation practices, involving a broader community of people, organizations, experts, and interest groups, could help scientists, regulators, and other stakeholders address these complex, value-laden concerns related to gene-editing of plants with and for society. Frontiers Media S.A. 2018-12-21 /pmc/articles/PMC6308909/ /pubmed/30622546 http://dx.doi.org/10.3389/fpls.2018.01874 Text en Copyright © 2018 Agapito-Tenfen, Okoli, Bernstein, Wikmark and Myhr. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Agapito-Tenfen, Sarah Z.
Okoli, Arinze S.
Bernstein, Michael J.
Wikmark, Odd-Gunnar
Myhr, Anne I.
Revisiting Risk Governance of GM Plants: The Need to Consider New and Emerging Gene-Editing Techniques
title Revisiting Risk Governance of GM Plants: The Need to Consider New and Emerging Gene-Editing Techniques
title_full Revisiting Risk Governance of GM Plants: The Need to Consider New and Emerging Gene-Editing Techniques
title_fullStr Revisiting Risk Governance of GM Plants: The Need to Consider New and Emerging Gene-Editing Techniques
title_full_unstemmed Revisiting Risk Governance of GM Plants: The Need to Consider New and Emerging Gene-Editing Techniques
title_short Revisiting Risk Governance of GM Plants: The Need to Consider New and Emerging Gene-Editing Techniques
title_sort revisiting risk governance of gm plants: the need to consider new and emerging gene-editing techniques
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308909/
https://www.ncbi.nlm.nih.gov/pubmed/30622546
http://dx.doi.org/10.3389/fpls.2018.01874
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