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Reconstructing high-resolution chromosome three-dimensional structures by Hi-C complex networks
BACKGROUND: Hi-C data have been widely used to reconstruct chromosomal three-dimensional (3D) structures. One of the key limitations of Hi-C is the unclear relationship between spatial distance and the number of Hi-C contacts. Many methods used a fixed parameter when converting the number of Hi-C co...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309071/ https://www.ncbi.nlm.nih.gov/pubmed/30591009 http://dx.doi.org/10.1186/s12859-018-2464-z |