The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?

The SMILES trial showed substantial improvement of depressive symptoms following seven consultations on healthy dieting. The very large effect size on depression reduction seems remarkable and we suggest that selectively induced expectancy and a loss of blinding have contributed to the observed effe...

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Detalles Bibliográficos
Autores principales: Molendijk, Marc L., Fried, Eiko I., Van der Does, Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309075/
https://www.ncbi.nlm.nih.gov/pubmed/30591065
http://dx.doi.org/10.1186/s12916-018-1221-5
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author Molendijk, Marc L.
Fried, Eiko I.
Van der Does, Willem
author_facet Molendijk, Marc L.
Fried, Eiko I.
Van der Does, Willem
author_sort Molendijk, Marc L.
collection PubMed
description The SMILES trial showed substantial improvement of depressive symptoms following seven consultations on healthy dieting. The very large effect size on depression reduction seems remarkable and we suggest that selectively induced expectancy and a loss of blinding have contributed to the observed effect.
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spelling pubmed-63090752019-01-03 The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect? Molendijk, Marc L. Fried, Eiko I. Van der Does, Willem BMC Med Correspondence The SMILES trial showed substantial improvement of depressive symptoms following seven consultations on healthy dieting. The very large effect size on depression reduction seems remarkable and we suggest that selectively induced expectancy and a loss of blinding have contributed to the observed effect. BioMed Central 2018-12-28 /pmc/articles/PMC6309075/ /pubmed/30591065 http://dx.doi.org/10.1186/s12916-018-1221-5 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Correspondence
Molendijk, Marc L.
Fried, Eiko I.
Van der Does, Willem
The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
title The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
title_full The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
title_fullStr The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
title_full_unstemmed The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
title_short The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
title_sort smiles trial: do undisclosed recruitment practices explain the remarkably large effect?
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309075/
https://www.ncbi.nlm.nih.gov/pubmed/30591065
http://dx.doi.org/10.1186/s12916-018-1221-5
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