Cargando…

Heterozygosity testing and multiplex DNA panel screening as a potential tool to monitor health and inbreeding in a small, closed dog population

BACKGROUND: Selective breeding in populations with a limited effective population size may result in a loss of genetic diversity, which can cause an increased concentration of specific disease liability genes. The Dutch Shepherd Dog (DSD) in the Netherlands is an example of such a breed with a small...

Descripción completa

Detalles Bibliográficos
Autores principales:	Keijser, S. F. A., Fieten, H., Vos-Loohuis, M., Piek, C. J., Anderson, H., Donner, J., Scholten, I., Nielen, M., Hesselink, J. W., van Steenbeek, F. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309085/ https://www.ncbi.nlm.nih.gov/pubmed/30607250 http://dx.doi.org/10.1186/s40575-018-0068-6

Ejemplares similares

A knockout mutation associated with juvenile paroxysmal dyskinesia in Markiesje dogs indicates SOD1 pleiotropy
por: Mandigers, P. J. J., et al.
Publicado: (2021)

The effect of inbreeding, body size and morphology on health in dog breeds
por: Bannasch, Danika, et al.
Publicado: (2021)

A Review of the Implications of Heterozygosity and Inbreeding on Germplasm Biodiversity and Its Conservation in the Silkworm, Bombyx mori
por: Jingade, A.H., et al.
Publicado: (2011)

SNP heterozygosity, relatedness and inbreeding of whole genomes from the isolated population of the Faroe Islands
por: Gislason, Hannes
Publicado: (2023)

A novel IBA57 variant is associated with mitochondrial iron–sulfur protein deficiency and necrotizing myelopathy in dogs
por: Mandigers, Paul J. J., et al.
Publicado: (2023)

Investigation of Genetic Modifiers of Copper Toxicosis in Labrador Retrievers
por: Wu, Xiaoyan, et al.
Publicado: (2020)

A loss of heterozygosity, a loss in competition? The effects of inbreeding, pre‐ and postnatal conditions on nestling development
por: de Boer, Raïssa A., et al.
Publicado: (2016)

Improved estimation of inbreeding and kinship in pigs using optimized SNP panels
por: Lopes, Marcos S, et al.
Publicado: (2013)

Inbreeding Avoidance by Recognition of Close Kin in the Pea Aphid, Acyrthosiphon pisum
por: Huang, Ming H., et al.
Publicado: (2012)

Using heterozygosity–fitness correlations to study inbreeding depression in an isolated population of white-tailed deer founded by few individuals
por: Brommer, Jon E, et al.
Publicado: (2015)

The Two Main Forms of Histiocytic Sarcoma in the Predisposed Flatcoated Retriever Dog Display Variation in Gene Expression
por: Boerkamp, Kim M., et al.
Publicado: (2014)

Opposition to Inbreeding Between Close Kin Reflects Inclusive Fitness Costs
por: Antfolk, Jan, et al.
Publicado: (2018)

Inbreeding depression due to recent and ancient inbreeding in Dutch Holstein–Friesian dairy cattle
por: Doekes, Harmen P., et al.
Publicado: (2019)

The existence of species rests on a metastable equilibrium between inbreeding and outbreeding. An essay on the close relationship between speciation, inbreeding and recessive mutations
por: Joly, Etienne
Publicado: (2011)

Resolving the conundrum of inbreeding depression but no inbreeding avoidance: Estimating sex‐specific selection on inbreeding by song sparrows (Melospiza melodia)
por: Reid, Jane M., et al.
Publicado: (2015)

Inbreeding Avoidance Influences the Viability of Reintroduced Populations of African Wild Dogs (Lycaon pictus)
por: Becker, Penny A., et al.
Publicado: (2012)

Nonequivalent lethal equivalents: Models and inbreeding metrics for unbiased estimation of inbreeding load
por: Nietlisbach, Pirmin, et al.
Publicado: (2018)

The effect of inbreeding rate on fitness, inbreeding depression and heterosis over a range of inbreeding coefficients
por: Pekkala, Nina, et al.
Publicado: (2014)

Loss of heterozygosity and microsatellite instability in hepatocellular carcinoma in Taiwan
por: Sheu, J-C, et al.
Publicado: (1999)

Recent breeding history of dog breeds in Sweden: modest rates of inbreeding, extensive loss of genetic diversity and lack of correlation between inbreeding and health
por: Jansson, M, et al.
Publicado: (2014)

Altered Subcellular Localization of Heat Shock Protein 90 Is Associated with Impaired Expression of the Aryl Hydrocarbon Receptor Pathway in Dogs
por: van Steenbeek, Frank G., et al.
Publicado: (2013)

Genome-Wide Estimates of Coancestry and Inbreeding in a Closed Herd of Ancient Iberian Pigs
por: Saura, María, et al.
Publicado: (2013)

What Happens after Inbreeding Avoidance? Inbreeding by Rejected Relatives and the Inclusive Fitness Benefit of Inbreeding Avoidance
por: Duthie, A. Bradley, et al.
Publicado: (2015)

Genetic Basis of Dilated Cardiomyopathy in Dogs and Its Potential as a Bidirectional Model
por: Gaar-Humphreys, Karen R., et al.
Publicado: (2022)

An isolated white‐tailed deer (Odocoileus virginianus) population on St. John, US Virgin Islands shows low inbreeding and comparable heterozygosity to other larger populations
por: Nelson, Suzanne L., et al.
Publicado: (2021)

Inbreeding, inbreeding depression, and infidelity in a cooperatively breeding bird
por: Hajduk, Gabriela K., et al.
Publicado: (2018)

A comparison of marker-based estimators of inbreeding and inbreeding depression
por: Caballero, Armando, et al.
Publicado: (2022)

A Contracted DNA Repeat in LHX3 Intron 5 Is Associated with Aberrant Splicing and Pituitary Dwarfism in German Shepherd Dogs
por: Voorbij, Annemarie M. W. Y., et al.
Publicado: (2011)

Investigating inbreeding in the turkey (Meleagris gallopavo) genome
por: Adams, Sarah M., et al.
Publicado: (2021)

Close inbreeding and low genetic diversity in Inner Asian human populations despite geographical exogamy
por: Marchi, Nina, et al.
Publicado: (2018)

Founder effects on trans-generational dynamics of closed inbreeding lineages of the predatory mite Phytoseiulus persimilis
por: Çekin, Demet, et al.
Publicado: (2019)

How Depressing Is Inbreeding? A Meta-Analysis of 30 Years of Research on the Effects of Inbreeding in Livestock
por: Doekes, Harmen P., et al.
Publicado: (2021)

No evidence of inbreeding depression in a Tasmanian devil insurance population despite significant variation in inbreeding
por: Gooley, Rebecca, et al.
Publicado: (2017)

Demographic assessment of the Dalmatian dog – effective population size, linkage disequilibrium and inbreeding coefficients
por: Vasiliadis, Danae, et al.
Publicado: (2020)

The German Shorthair Pointer Dog Breed (Canis lupus familiaris): Genomic Inbreeding and Variability
por: Boccardo, Antonio, et al.
Publicado: (2020)

Estimating selection on the act of inbreeding in a population with strong inbreeding depression
por: Troianou, Eva, et al.
Publicado: (2018)

Impact of Inbreeding and Ancestral Inbreeding on Longevity Traits in German Brown Cows
por: Wirth, Anna, et al.
Publicado: (2023)

A multiplex quantitative real-time polymerase chain reaction panel for detecting neurologic pathogens in dogs with meningoencephalitis
por: Han, Jae-Ik, et al.
Publicado: (2015)

Lethal gene drive selects inbreeding
por: Bull, James J
Publicado: (2016)

Inbreeding depression in red deer calves
por: Walling, Craig A, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ti3b4nkptr23hptpfmbmv3nffl