Cargando…

Retinal Morphometric Markers of Crystallized and Fluid Intelligence Among Adults With Overweight and Obesity

Objective: To investigate the relationship between retinal morphometric measures and intellectual abilities among adults with overweight and obesity. Methods: Adults between 25 and 45 years (N = 55, 38 females) with overweight or obesity (BMI ≥ 25.0 kg/m(2)) underwent an optical coherence tomography...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Alicia R., Robbs, Connor M., Edwards, Caitlyn G., Walk, Anne M., Thompson, Sharon V., Reeser, Ginger E., Holscher, Hannah D., Khan, Naiman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309102/
https://www.ncbi.nlm.nih.gov/pubmed/30622502
http://dx.doi.org/10.3389/fpsyg.2018.02650
_version_ 1783383340684935168
author Jones, Alicia R.
Robbs, Connor M.
Edwards, Caitlyn G.
Walk, Anne M.
Thompson, Sharon V.
Reeser, Ginger E.
Holscher, Hannah D.
Khan, Naiman A.
author_facet Jones, Alicia R.
Robbs, Connor M.
Edwards, Caitlyn G.
Walk, Anne M.
Thompson, Sharon V.
Reeser, Ginger E.
Holscher, Hannah D.
Khan, Naiman A.
author_sort Jones, Alicia R.
collection PubMed
description Objective: To investigate the relationship between retinal morphometric measures and intellectual abilities among adults with overweight and obesity. Methods: Adults between 25 and 45 years (N = 55, 38 females) with overweight or obesity (BMI ≥ 25.0 kg/m(2)) underwent an optical coherence tomography (OCT) scan to assess retinal nerve fiber layer (RNFL) volume, ganglion cell layer (GCL) volume, macular volume, and central foveal thickness. Dual-Energy X-ray absorptiometry was used to assess whole-body adiposity (% Fat). The Kaufman Brief Intelligence Test-2 was used to assess general intelligence (IQ), fluid, and crystallized intelligence. Hierarchical linear regression analyses were performed to examine relationships between adiposity and intelligence measures following adjustment of relevant demographic characteristics and degree of adiposity (i.e., % Fat). Results: Although initial bivariate correlations indicated that % Fat was inversely related to fluid intelligence, this relationship was mitigated by inclusion of other demographic factors, including age, sex, and education level. Regression analyses for primary outcomes revealed that RNFL was positively related to IQ and fluid intelligence. However, only GCL was positively related to crystallized intelligence. Conclusion: This work provides novel data linking specific retinal morphometric measures – assessed using OCT – to intellectual abilities among adults with overweight and obesity. Clinical Trial Registration: www.clinicaltrials.gov, identifier NCT02740439.
format Online
Article
Text
id pubmed-6309102
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-63091022019-01-08 Retinal Morphometric Markers of Crystallized and Fluid Intelligence Among Adults With Overweight and Obesity Jones, Alicia R. Robbs, Connor M. Edwards, Caitlyn G. Walk, Anne M. Thompson, Sharon V. Reeser, Ginger E. Holscher, Hannah D. Khan, Naiman A. Front Psychol Psychology Objective: To investigate the relationship between retinal morphometric measures and intellectual abilities among adults with overweight and obesity. Methods: Adults between 25 and 45 years (N = 55, 38 females) with overweight or obesity (BMI ≥ 25.0 kg/m(2)) underwent an optical coherence tomography (OCT) scan to assess retinal nerve fiber layer (RNFL) volume, ganglion cell layer (GCL) volume, macular volume, and central foveal thickness. Dual-Energy X-ray absorptiometry was used to assess whole-body adiposity (% Fat). The Kaufman Brief Intelligence Test-2 was used to assess general intelligence (IQ), fluid, and crystallized intelligence. Hierarchical linear regression analyses were performed to examine relationships between adiposity and intelligence measures following adjustment of relevant demographic characteristics and degree of adiposity (i.e., % Fat). Results: Although initial bivariate correlations indicated that % Fat was inversely related to fluid intelligence, this relationship was mitigated by inclusion of other demographic factors, including age, sex, and education level. Regression analyses for primary outcomes revealed that RNFL was positively related to IQ and fluid intelligence. However, only GCL was positively related to crystallized intelligence. Conclusion: This work provides novel data linking specific retinal morphometric measures – assessed using OCT – to intellectual abilities among adults with overweight and obesity. Clinical Trial Registration: www.clinicaltrials.gov, identifier NCT02740439. Frontiers Media S.A. 2018-12-21 /pmc/articles/PMC6309102/ /pubmed/30622502 http://dx.doi.org/10.3389/fpsyg.2018.02650 Text en Copyright © 2018 Jones, Robbs, Edwards, Walk, Thompson, Reeser, Holscher and Khan. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychology
Jones, Alicia R.
Robbs, Connor M.
Edwards, Caitlyn G.
Walk, Anne M.
Thompson, Sharon V.
Reeser, Ginger E.
Holscher, Hannah D.
Khan, Naiman A.
Retinal Morphometric Markers of Crystallized and Fluid Intelligence Among Adults With Overweight and Obesity
title Retinal Morphometric Markers of Crystallized and Fluid Intelligence Among Adults With Overweight and Obesity
title_full Retinal Morphometric Markers of Crystallized and Fluid Intelligence Among Adults With Overweight and Obesity
title_fullStr Retinal Morphometric Markers of Crystallized and Fluid Intelligence Among Adults With Overweight and Obesity
title_full_unstemmed Retinal Morphometric Markers of Crystallized and Fluid Intelligence Among Adults With Overweight and Obesity
title_short Retinal Morphometric Markers of Crystallized and Fluid Intelligence Among Adults With Overweight and Obesity
title_sort retinal morphometric markers of crystallized and fluid intelligence among adults with overweight and obesity
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309102/
https://www.ncbi.nlm.nih.gov/pubmed/30622502
http://dx.doi.org/10.3389/fpsyg.2018.02650
work_keys_str_mv AT jonesaliciar retinalmorphometricmarkersofcrystallizedandfluidintelligenceamongadultswithoverweightandobesity
AT robbsconnorm retinalmorphometricmarkersofcrystallizedandfluidintelligenceamongadultswithoverweightandobesity
AT edwardscaitlyng retinalmorphometricmarkersofcrystallizedandfluidintelligenceamongadultswithoverweightandobesity
AT walkannem retinalmorphometricmarkersofcrystallizedandfluidintelligenceamongadultswithoverweightandobesity
AT thompsonsharonv retinalmorphometricmarkersofcrystallizedandfluidintelligenceamongadultswithoverweightandobesity
AT reesergingere retinalmorphometricmarkersofcrystallizedandfluidintelligenceamongadultswithoverweightandobesity
AT holscherhannahd retinalmorphometricmarkersofcrystallizedandfluidintelligenceamongadultswithoverweightandobesity
AT khannaimana retinalmorphometricmarkersofcrystallizedandfluidintelligenceamongadultswithoverweightandobesity