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Synthesis and Evaluation of a New Type of Small Molecule Epigenetic Modulator Containing Imidazo[1,2-b][1,2,4]triazole Motif

Epigenetic modifications such as DNA methylation is important for many cellular processes, such as cell differentiation and cell death. The disorder of epigenetic state is closely related to human diseases, especially cancers. DNA methylation is a well-characterized epigenetic modification which is...

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Detalles Bibliográficos
Autores principales:	Wu, Fan, Zhang, Jing, Shang, Erchang, Zhang, Junzhi, Li, Xiang, Zhu, Bing, Lei, Xiaoguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309140/ https://www.ncbi.nlm.nih.gov/pubmed/30627529 http://dx.doi.org/10.3389/fchem.2018.00642

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