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Association between genetic polymorphisms of CYP2C9 and VKORC1 and safety and efficacy of warfarin: Results of a 5 years audit

OBJECTIVE: Genetic polymorphisms of CYP2C9 and VKORC1 play major role in pharmacokinetics and pharmacodynamics of warfarin, respectively. Purpose of our study was to assess the utility of pretesting patients for the above mutations in predicting tendency for bleeding and achieving target INR. METHOD...

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Detalles Bibliográficos
Autores principales:	Biswas, Mansij, Bendkhale, Shital R., Deshpande, Siddharth P., Thaker, Saket J., Kulkarni, Dwarkanath V., Bhatia, Shobna J., Rajadhyaksha, Anjali G., Gogtay, Nithya J., Thatte, Urmila M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Clinical and Preventive Cardiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309143/ https://www.ncbi.nlm.nih.gov/pubmed/30595245 http://dx.doi.org/10.1016/j.ihj.2018.02.005

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