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Poly(A) polymerase (PAP) diversity in gene expression – Star-PAP vs canonical PAP
Almost all eukaryotic mRNAs acquire a poly(A) tail at the 3′-end by a concerted RNA processing event: cleavage and polyadenylation. The canonical PAP, PAPα, was considered the only nuclear PAP involved in general polyadenylation of mRNAs. A phosphoinositide-modulated nuclear PAP, Star-PAP, was then...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309179/ https://www.ncbi.nlm.nih.gov/pubmed/24873880 http://dx.doi.org/10.1016/j.febslet.2014.05.029 |