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Requirement for CD40/CD40L Interactions for Development of Autoimmunity Differs Depending on Specific Checkpoint and Costimulatory Pathways

CD40/CD40L interactions play a critical role in immunity and autoimmunity. In this study, we sought to understand the requirement for CD40 signaling in the programmed cell death-1 (PD-1) checkpoint and CD28 costimulatory pathways important for maintenance of peripheral tolerance. Blocking either pat...

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Detalles Bibliográficos
Autores principales:	Voynova, Elisaveta, Mahmoud, Tamer, Woods, Lucas T., Weisman, Gary A., Ettinger, Rachel, Braley-Mullen, Helen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309431/ https://www.ncbi.nlm.nih.gov/pubmed/30607385 http://dx.doi.org/10.4049/immunohorizons.1700069

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