Cargando…

Enter the Matrix: Factorization Uncovers Knowledge from Omics

Omics data contain signals from the molecular, physical, and kinetic inter- and intracellular interactions that control biological systems. Matrix factorization (MF) techniquescan reveal low-dimensional structure from high-dimensional data that reflect these interactions. These techniques can uncove...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stein-O’Brien, Genevieve L., Arora, Raman, Culhane, Aedin C., Favorov, Alexander V., Garmire, Lana X., Greene, Casey S., Goff, Loyal A., Li, Yifeng, Ngom, Aloune, Ochs, Michael F., Xu, Yanxun, Fertig, Elana J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309559/ https://www.ncbi.nlm.nih.gov/pubmed/30143323 http://dx.doi.org/10.1016/j.tig.2018.07.003

Ejemplares similares

Hybrid Modeling of Cell Signaling and Transcriptional Reprogramming and Its Application in C. elegans Development
por: Fertig, Elana J., et al.
Publicado: (2011)

Matrix factorization and transfer learning uncover regulatory biology across multiple single-cell ATAC-seq data sets
por: Erbe, Rossin, et al.
Publicado: (2020)

A multivariate approach to the integration of multi-omics datasets
por: Meng, Chen, et al.
Publicado: (2014)

Community-wide hackathons to identify central themes in single-cell multi-omics
por: Lê Cao, Kim-Anh, et al.
Publicado: (2021)

Author Correction: Community-wide hackathons to identify central themes in single-cell multi-omics
por: Cao, Kim-Anh Lê, et al.
Publicado: (2021)

More Is Better: Recent Progress in Multi-Omics Data Integration Methods
por: Huang, Sijia, et al.
Publicado: (2017)

MOGSA: Integrative Single Sample Gene-set Analysis of Multiple Omics Data
por: Meng, Chen, et al.
Publicado: (2019)

Dimension reduction techniques for the integrative analysis of multi-omics data
por: Meng, Chen, et al.
Publicado: (2016)

Computational Methods for Single-cell Multi-omics Integration and Alignment
por: Stanojevic, Stefan, et al.
Publicado: (2022)

Integrated time course omics analysis distinguishes immediate therapeutic response from acquired resistance
por: Stein-O’Brien, Genevieve, et al.
Publicado: (2018)

Cox-nnet: An artificial neural network method for prognosis prediction of high-throughput omics data
por: Ching, Travers, et al.
Publicado: (2018)

Spatial correlation statistics enable transcriptome-wide characterization of RNA structure binding
por: Busa, Veronica F., et al.
Publicado: (2021)

Computational reconstruction of the signalling networks surrounding implanted biomaterials from single-cell transcriptomics
por: Cherry, Christopher, et al.
Publicado: (2021)

Review of "bioinformatics basics: applications in biological science and medicine" by Buehler & Rashidi
por: Culhane, Aedín
Publicado: (2006)

DeepProg: an ensemble of deep-learning and machine-learning models for prognosis prediction using multi-omics data
por: Poirion, Olivier B., et al.
Publicado: (2021)

Using single-cell multiple omics approaches to resolve tumor heterogeneity
por: Ortega, Michael A., et al.
Publicado: (2017)

AGA: Interactive pipeline for reproducible gene expression and DNA methylation data analyses
por: Considine, Michael, et al.
Publicado: (2015)

Transcriptomic forecasting with neural ordinary differential equations
por: Erbe, Rossin, et al.
Publicado: (2023)

Digitizing omics profiles by divergence from a baseline
por: Dinalankara, Wikum, et al.
Publicado: (2018)

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network
por: Fertig, Elana J., et al.
Publicado: (2016)

Ret deficiency decreases neural crest progenitor proliferation and restricts fate potential during enteric nervous system development
por: Vincent, Elizabeth, et al.
Publicado: (2023)

Impact of Data Preprocessing on Integrative Matrix Factorization of Single Cell Data
por: Hsu, Lauren L., et al.
Publicado: (2020)

Correspondence analysis for dimension reduction, batch integration, and visualization of single-cell RNA-seq data
por: Hsu, Lauren L., et al.
Publicado: (2023)

A Mentee’s Baby Registry: Supporting New Academic Parents in 2020
por: Fertig, Elana J.
Publicado: (2020)

Integrated omics in Drosophila uncover a circadian kinome
por: Wang, Chenwei, et al.
Publicado: (2020)

Epigenetic regulation of gene expression in cancer: techniques, resources and analysis
por: Kagohara, Luciane T, et al.
Publicado: (2017)

DNA methylation regulates TMEM16A/ANO1 expression through multiple CpG islands in head and neck squamous cell carcinoma
por: Finegersh, Andrey, et al.
Publicado: (2017)

Cross-platform comparison and visualisation of gene expression data using co-inertia analysis
por: Culhane, Aedín C, et al.
Publicado: (2003)

Uncovering the impacts of alternative splicing on the proteome with current omics techniques
por: Reixachs‐Solé, Marina, et al.
Publicado: (2022)

Multi-Omics Uncover Neonatal Cecal Cell Development Potentials
por: Chen, Liang, et al.
Publicado: (2022)

Omics Approaches in Uncovering Molecular Evolution and Physiology of Botanical Carnivory
por: Baharin, Anis, et al.
Publicado: (2023)

Corrigendum to: Recommendations to enhance rigor and reproducibility in biomedical research
por: Brito, Jaqueline J, et al.
Publicado: (2020)

Recommendations to enhance rigor and reproducibility in biomedical research
por: Brito, Jaqueline J, et al.
Publicado: (2020)

From Hawaii to PECASE award: tips of success from a female bioinformatician
por: Garmire, Lana X.
Publicado: (2019)

Mentorship is not co-authorship: a revisit to mentorship
por: Garmire, Lana X.
Publicado: (2021)

Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data
por: Jeffery, Ian B, et al.
Publicado: (2006)

Multi-Omics Uncover the Mechanism of Wheat under Heavy Metal Stress
por: Zhou, Min, et al.
Publicado: (2022)

Widespread redundancy in -omics profiles of cancer mutation states
por: Crawford, Jake, et al.
Publicado: (2022)

The Emerging Oilseed Crop Sesamum indicum Enters the “Omics” Era
por: Dossa, Komivi, et al.
Publicado: (2017)

Quantifying the Dynamics of Coupled Networks of Switches and Oscillators
por: Francis, Matthew R., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_di673jq8f7dakukdcddb4mjtih