Cargando…

Heart transplantation after the circulatory death; The ethical dilemma

Donors after brain death (DBD) have been the major source of organ donation due to good perfusion of the organs. However, owing to the mismatch in demand and supply of the organ donors and recipients, donors after circulatory death (DCDDs) has increased recently all over the world. Kidneys, liver, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Marsia, Shayan, Khan, Ariba, Khan, Maryam, Ahmed, Saba, Hayat, Javeria, Minhas, Abdul Mannan Khan, Mirza, Samir, Asmi, Nisar, Constantin, Jonathon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309566/
https://www.ncbi.nlm.nih.gov/pubmed/30595305
http://dx.doi.org/10.1016/j.ihj.2018.08.010
_version_ 1783383373631193088
author Marsia, Shayan
Khan, Ariba
Khan, Maryam
Ahmed, Saba
Hayat, Javeria
Minhas, Abdul Mannan Khan
Mirza, Samir
Asmi, Nisar
Constantin, Jonathon
author_facet Marsia, Shayan
Khan, Ariba
Khan, Maryam
Ahmed, Saba
Hayat, Javeria
Minhas, Abdul Mannan Khan
Mirza, Samir
Asmi, Nisar
Constantin, Jonathon
author_sort Marsia, Shayan
collection PubMed
description Donors after brain death (DBD) have been the major source of organ donation due to good perfusion of the organs. However, owing to the mismatch in demand and supply of the organ donors and recipients, donors after circulatory death (DCDDs) has increased recently all over the world. Kidneys, liver, and lungs are being used for transplantation from DCDDs. Recently, heart transplantation from DCDDs has been started, which is under the firestorm of scrutiny by the ethicists. The ethical dilemma revolves around the question whether the donors are actually dead when they are declared dead by cardiocirculatory death criteria for organ procurement. The subsequent literature review addresses all the perspectives by differentiating between the donation methods known as DBDs and DCDDs, explaining the implications of the dead-donor rule on the organ donation pool, and categorizing the determinants of death leading to separation of the arguments under the two methods of donations.
format Online
Article
Text
id pubmed-6309566
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-63095662019-12-01 Heart transplantation after the circulatory death; The ethical dilemma Marsia, Shayan Khan, Ariba Khan, Maryam Ahmed, Saba Hayat, Javeria Minhas, Abdul Mannan Khan Mirza, Samir Asmi, Nisar Constantin, Jonathon Indian Heart J Review Article Donors after brain death (DBD) have been the major source of organ donation due to good perfusion of the organs. However, owing to the mismatch in demand and supply of the organ donors and recipients, donors after circulatory death (DCDDs) has increased recently all over the world. Kidneys, liver, and lungs are being used for transplantation from DCDDs. Recently, heart transplantation from DCDDs has been started, which is under the firestorm of scrutiny by the ethicists. The ethical dilemma revolves around the question whether the donors are actually dead when they are declared dead by cardiocirculatory death criteria for organ procurement. The subsequent literature review addresses all the perspectives by differentiating between the donation methods known as DBDs and DCDDs, explaining the implications of the dead-donor rule on the organ donation pool, and categorizing the determinants of death leading to separation of the arguments under the two methods of donations. Elsevier 2018-12 2018-08-20 /pmc/articles/PMC6309566/ /pubmed/30595305 http://dx.doi.org/10.1016/j.ihj.2018.08.010 Text en © 2018 Cardiological Society of India. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Marsia, Shayan
Khan, Ariba
Khan, Maryam
Ahmed, Saba
Hayat, Javeria
Minhas, Abdul Mannan Khan
Mirza, Samir
Asmi, Nisar
Constantin, Jonathon
Heart transplantation after the circulatory death; The ethical dilemma
title Heart transplantation after the circulatory death; The ethical dilemma
title_full Heart transplantation after the circulatory death; The ethical dilemma
title_fullStr Heart transplantation after the circulatory death; The ethical dilemma
title_full_unstemmed Heart transplantation after the circulatory death; The ethical dilemma
title_short Heart transplantation after the circulatory death; The ethical dilemma
title_sort heart transplantation after the circulatory death; the ethical dilemma
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309566/
https://www.ncbi.nlm.nih.gov/pubmed/30595305
http://dx.doi.org/10.1016/j.ihj.2018.08.010
work_keys_str_mv AT marsiashayan hearttransplantationafterthecirculatorydeaththeethicaldilemma
AT khanariba hearttransplantationafterthecirculatorydeaththeethicaldilemma
AT khanmaryam hearttransplantationafterthecirculatorydeaththeethicaldilemma
AT ahmedsaba hearttransplantationafterthecirculatorydeaththeethicaldilemma
AT hayatjaveria hearttransplantationafterthecirculatorydeaththeethicaldilemma
AT minhasabdulmannankhan hearttransplantationafterthecirculatorydeaththeethicaldilemma
AT mirzasamir hearttransplantationafterthecirculatorydeaththeethicaldilemma
AT asminisar hearttransplantationafterthecirculatorydeaththeethicaldilemma
AT constantinjonathon hearttransplantationafterthecirculatorydeaththeethicaldilemma