Phenotypic Characterization of Murine Models of Cerebral Cavernous Malformations

Cerebral cavernous malformations (CCMs) are clusters of dilated capillaries that affect around 0.5% of the population. CCMs exist in two forms, sporadic and familial. Mutations in 3 documented genes, KRIT1 (CCM1), CCM2 and PDCD10 (CCM3), cause the autosomal dominant form of the disease, and somatic...

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Detalles Bibliográficos
Autores principales: Zeineddine, Hussein A., Girard, Romuald, Saadat, Laleh, Shen, Le, Lightle, Rhonda, Moore, Thomas, Cao, Ying, Hobson, Nick, Shenkar, Robert, Avner, Kenneth, Chaudager, Kiranj, Koskimäki, Janne, Polster, Sean P., Fam, Maged D., Shi, Changbin, Lopez-Ramirez, Miguel Alejandro, Tang, Alan T., Gallione, Carol, Kahn, Mark L., Ginsberg, Mark, Marchuk, Douglas A., Awad, Issam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309944/
https://www.ncbi.nlm.nih.gov/pubmed/29946133
http://dx.doi.org/10.1038/s41374-018-0030-y

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