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The Importance of mTOR Trafficking for Human Skeletal Muscle Translational Control

The mechanistic target of rapamycin (mTOR) is a central regulator of muscle protein synthesis, and its activation has long been attributed to its translocation to the lysosome. Here, we present a novel model of mTOR activation in skeletal muscle where the translocation of mTOR and the lysosome towar...

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Detalles Bibliográficos
Autores principales: Hodson, Nathan, Philp, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310455/
https://www.ncbi.nlm.nih.gov/pubmed/30334852
http://dx.doi.org/10.1249/JES.0000000000000173

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