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Interferons Transcriptionally Up-Regulate MLKL Expression in Cancer Cells()
Interferons (IFNs) are key players in the tumor immune response and act by inducing the expression of IFN-stimulated genes (ISGs). Here, we identify the mixed-lineage kinase domain-like pseudokinase (MLKL) as an ISG in various cancer cell lines. Both type I and type II IFNs increase the expression o...
Autores principales: | Knuth, Anne-Kathrin, Rösler, Stefanie, Schenk, Barbara, Kowald, Lisa, van Wijk, Sjoerd J.L., Fulda, Simone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310689/ https://www.ncbi.nlm.nih.gov/pubmed/30521981 http://dx.doi.org/10.1016/j.neo.2018.11.002 |
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